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The current multistep carcinogenesis models of colon cancer do not fully capture the genetic heterogeneity of the disease, which is additionally complicated by the presence of passenger and driver genetic alterations. The aim of the present study was to select in the context of this significant hete...
ORGANISM(S): Homo sapiens 
The ETS transcription factor GABPA controls cell migration in breast epithelial cells through targeting a cohort of genes, independently from another family member ELK1, and thereby achieves biological specificity. Here, both direct and indirect target genes for GABPA are identified by siRNA silenci...
ORGANISM(S): Homo sapiens 
The Salicaceae family is of growing interest in the study of dioecy in plants because the sex determination region (SDR) has been shown to be highly dynamic, with differing locations and heterogametic systems across taxa. Previous studies investigating the mechanisms regulating sex in the genus Sali...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2023-02-01 | MSV000091180 | MassIVE
The kidney contains distinct glomerular and tubulointerstitial compartments with diverse cell types and extracellular matrix components. Glomerular disease is characterized by excess matrix deposition and the loss of filtration barrier integrity. The role of immune cells in glomerular disease is cru...
ORGANISM(S): Mus musculus 
To comprehensively profile cell types in the human retina, we performed single cell RNA-sequencing on 20,009 cells obtained post-mortem from three donors and compiled a reference transcriptome atlas. Using unsupervised clustering analysis, we identified 18 transcriptionally distinct clusters represe...
ORGANISM(S): Homo sapiens 
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