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Cohesin is implicated in establishing tissue-specific DNA loops that target enhancers to promoters, and also localizes to sites bound by the insulator protein CTCF, which blocks enhancer-promoter communication. However, cohesin-associated interactions have not been characterized on a genome-wide sca...
ORGANISM(S): Mus musculus 
We performed RNA-sequencing in LSK cells (Lin(neg)/c-Kit(+)/Sca-1(+)) from shRNA mice carrying an shRNA for Renilla, Smc1a or Stag2. RNA-sequencing control (Renilla) and cohesin (Smc1a and Stag2) knockdown cells.
ORGANISM(S): Mus musculus 
SMC1A, CTCF and MITF level on chromatin after knockdown of NIPBL in melanoma cell line
This study examines the DNA binding regions of SMC1A, a subunit of the Cohesin complex, in undifferentiated human keratinocytes.
ORGANISM(S): Homo sapiens 
2017-10-01 | GSE85526 | GEO
The X-linked chromatin modifier SMC1A is deregulated in lupus female monocytes and promotes autoimmunity [ChIP-Seq]
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