Extramedullary relapse (EM) of multiple myeloma (MM) is defined as infiltration of plasma cells (PC) outside of the bone marrow. EM is an aggressive form of the disease with a dismal outcome. We present cytogenetic findings of a 52-year-old female patient who was diagnosed with MM in 2008 and progr...
In this study, we evaluation of incidence of copy number abnormalities (CNAs) with high-desity CGH+SNP microarrays in cohort 26 patients with cervical tumors. Incidence of CNAs was copmared with clinical prognostic factors.
Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes. Epithelial-mesenchymal interaction between stromal fibroblasts and cancer cells influences the functional properties of tumor epithelium including the tumor progression and s...
In this paper, we demonstrated the possibility of effective utilization of oligonucleotide-based aCGH as a robust clinical tool for genome-wide scanning and detailed analysis of unbalanced genetic aberrations in 91 MM patients in combination with fluorescence in situ hybridization (FISH) in detectio...
In this study, we addressed the difference between adult fibroblasts developmentally originating from the ectomesenchyme and mesoderm at the scale of whole genome expression. Fibroblasts were collected from various body parts and types. This includes fibroblasts from the oral cavity, internal organs...
