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MetabolomicsCTH exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation
Macrophages play a crucial role in the inflammatory response to the human stomach pathogen Helicobacter pylori, which infects half of the world's population and causes gastric cancer. Recent studies have highlighted the importance of macrophage immunometabolism in their activation state and function...
2022-06-14 | MTBLS2851 | MetaboLights
MetabolomicsHypusination Orchestrates the Antimicrobial Response of Macrophages
Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...
2021-04-06 | MTBLS607 | MetaboLights
MetabolomicsMetabolomics Analysis Reveals Tissue-Specific Metabolite Compositions in Leaf Blade and Traps of Carnivorous Nepenthes Plants
Nepenthes is a genus of carnivorous plants that evolved a pitfall trap, the pitcher, to catch and digest insect prey to obtain additional nutrients. Each pitcher is part of the whole leaf, together with a leaf blade. These two completely different parts of the same organ were studied separately in a...
2020-07-10 | MTBLS1783 | MetaboLights
UnknownSeawi--a sea urchin piwi/argonaute family member is a component of MT-RNP complexes.
Not available
S-EPMC1370751 | biostudies-literature
TranscriptomicsInterference with ethylene perception at receptor level sheds light on auxin and transcriptional circuits associated with climacteric ripening of apple fruit (Malus x domestica Borkh.)
Apple (Malus x domestica Borkh.) is a model fruit species to study the metabolic changes occurring at the onset of ripening as well the physiological mechanism governed by the hormone ethylene. In this survey, to dissect the climacteric interplay in apple, a multidisciplinary approach was employed. ...
ORGANISM(S): Malus domestica 
2016-08-23 | E-GEOD-78745 | biostudies-arrayexpress
TranscriptomicsIntegrative approach combining transcriptomic assay with physical and metabolite analysis reveal novel clues about the regulatory mechanism governing the climacteric ripening physiology in apple (Malus x domestica Borkh.) [WGAA]
Apple (Malus x domestica Borkh.) is a model fruit species to study the metabolic changes occurring at the onset of ripening as well the physiological mechanism governed by the hormone ethylene. In this survey, to dissect the climacteric interplay in apple, a multidisciplinary approach was employed. ...
ORGANISM(S): Malus domestica 
2016-08-23 | E-GEOD-78744 | biostudies-arrayexpress
UnknownPeptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells.
Not available
S-EPMC12594172 | biostudies-literature
UnknownOverexpression of the oncostatin-M receptor in cervical squamous cell carcinoma is associated with epithelial-mesenchymal transition and poor overall survival.
Not available
S-EPMC4947707 | biostudies-literature
UnknownEarly intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial.
Not available
S-EPMC10189540 | biostudies-literature
UnknownPad size, orientation, and placement for defibrillation during basic life support: A systematic review.
Not available
S-EPMC12309583 | biostudies-literature
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