Sort   by:  
 Page size 
TranscriptomicsLong-range expression effects of CNV: insights from Smith-Magenis and Potocki-Lupski syndrome mouse model
To study the effect of structural changes on expression, we assessed gene expression in genomic disorder mouse models. Both a microdeletion and its reciprocal microduplication mapping to mouse chromosome 11 (MMU11), which model the rearrangements present in Smith-Magenis (SMS) and Potocki-Lupski (PT...
ORGANISM(S): Mus musculus 
2010-11-10 | E-GEOD-14802 | biostudies-arrayexpress
MetabolomicsCTH exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation
Macrophages play a crucial role in the inflammatory response to the human stomach pathogen Helicobacter pylori, which infects half of the world's population and causes gastric cancer. Recent studies have highlighted the importance of macrophage immunometabolism in their activation state and function...
2022-06-14 | MTBLS2851 | MetaboLights
MetabolomicsHypusination Orchestrates the Antimicrobial Response of Macrophages
Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...
2021-04-06 | MTBLS607 | MetaboLights
TranscriptomicsTranscription profiling time series toxicogenomic profiles in CD-1 mice after nontoxic and nonlethal hepatotoxic paracetamol administration
Effect of vehicle vs non-toxic and toxic paracetamol (151mg/kg and 529mg/kg) doses on the gene expression profile at 1, 4 and 24h in murine liver.
ORGANISM(S): Mus musculus 
2004-02-20 | E-MEXP-82 | biostudies-arrayexpress
UnknownHLA-DP on Epithelial Cells Enables Tissue Damage by NKp44<sup>+</sup> Natural Killer Cells in Ulcerative Colitis.
Not available
S-EPMC10529779 | biostudies-literature
TranscriptomicsRNA-seq of mouse embryonic stem cells with knockout of Nhlrc2 gene or addition of FINCA disease causing NHLRC2 p.Asp148Tyr variant
Fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA) (OMIM 618278) is a rare infantile-onset disease caused by variants in NHL repeat containing 2 (NHLRC2) gene. NHLRC2 is essential for mouse gastrulation (Hiltunen et al., 2022). Here, RNA sequencing was performed on four wild type (WT), f...
ORGANISM(S): Mus musculus 
2025-05-22 | E-MTAB-14174 | biostudies-arrayexpress
UnknownGenetic adaptation of Pseudomonas aeruginosa to the airways of cystic fibrosis patients is catalyzed by hypermutation.
Not available
S-EPMC2593214 | biostudies-literature
UnknownVitamin K Dependent Protection of Renal Function in Multi-ethnic Population Studies.
Not available
S-EPMC4776057 | biostudies-literature
TranscriptomicsHTCC1062 glucose versus no carbon log phase
The primary goal of this experiment is to examine the transcription profiles of HTCC1062 when grown in the presence or absence of D-glucose (30uM final concentration). Experiment confirmed activity of predicted glycolysis operon. Three biological replicates of HTCC1062 grown on glucose (30uM final c...
ORGANISM(S): Candidatus Pelagibacter ubique HTCC1062 
2010-05-16 | E-GEOD-14974 | biostudies-arrayexpress
TranscriptomicsTranscriptional Response to Iron Limitation in Pelagibacter ubique
We investigated the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation. Differential expression was observed for genes in iron acquisition and incorporation operons. SfuC in particular was 16 times higher in iron-limited cultures and encodes a periplasmic iron-bi...
ORGANISM(S): Candidatus Pelagibacter ubique HTCC1062 
2010-05-05 | E-GEOD-20962 | biostudies-arrayexpress
Sort   by:  
 Page size