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TranscriptomicsMKL1-dependent tenascin-C transcription
The aim of the experiment is to investigate whether megakaryoblastic leukemia factor-1 (MKL1) induces tenascin-C in normal mammary epithelial HC11 and tumor mammary epithelial 4T1 cell lines, as well as to identify other genes that are transcriptionally regulated by MKL1. For this purpose, we compar...
ORGANISM(S): Mus musculus 
2011-06-10 | E-MEXP-3232 | biostudies-arrayexpress
MetabolomicsUltra-High Mass Resolving Power, Mass Accuracy, and Dynamic Range MALDI Mass Spectrometry Imaging by 21-T FT-ICR MS

Detailed characterization of complex biological surfaces by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy and dynamic range. Fourier transform ion cyclotron resonance mass sp...

2022-01-28 | MTBLS3154 | MetaboLights
TranscriptomicsGenome-wide copy number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma
We studied 277 lymphoma samples (198 FL and 79 transformed FL [tFL]) using a single-nucleotide polymorphism array to identify the secondary chromosomal abnormalities that drive the development of FL and its transformation to diffuse large B-cell lymphoma. Affymetrix 250K NspI SNP arrays were perform...
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-67385 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
We have previously shown that HC11 mammary epithelial cells react strongly to the overexpression of megakaryoblastic leukemia-1 (Mkl1) with induction of tenascin-C expression. The present study was designed to find genes co-regulated with tenascin-C by Mkl1 in a SAP domain-dependent manner and witho...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-44907 | biostudies-arrayexpress
ProteomicsUrine protein composition of common bottlenose dolphins (Tursiops truncatus) in the Gulf of Mexico, USA
Urinary proteins provide valuable insights into renal health, with implications spanning human and domestic animal veterinary medical research. However, the field of marine mammal medicine lacks comprehensive studies on urine protein composition. This research aimed to fill this gap by 1) selecting ...
ORGANISM(S): Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus) 
2024-08-01 | PXD054283 | Pride
Lc-msms Urine Common bottlenose dolphin 
UnknownA Rare De Novo RAI1 Gene Mutation Affecting BDNF-Enhancer-Driven Transcription Activity Associated with Autism and Atypical Smith-Magenis Syndrome Presentation.
Not available
S-EPMC6023015 | biostudies-literature
TranscriptomicsIdentification of megakaryoblastic leukemia-1 (Mkl1) target genes in 4T1 mammary carcinoma cells
The present study was designed to identify Mkl1 target genes whose expression requires either the B1 site of Mkl1 and serum response factor (SRF), respectively, or the SAP domain of Mkl1. For this purpose, we obtained the transcriptomes of four stable 4T1 cell lines that either overexpress full leng...
ORGANISM(S): Mus musculus 
2016-07-15 | E-GEOD-59459 | biostudies-arrayexpress
UnknownSafety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab.
Not available
S-EPMC4878046 | biostudies-literature
UnknownEndothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress.
Not available
S-EPMC5714503 | biostudies-literature
UnknownHypothermia for Patients Requiring Evacuation of Subdural Hematoma: A Multicenter Randomized Clinical Trial.
Not available
S-EPMC8964656 | biostudies-literature
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