Sort   by:  
 Page size 
TranscriptomicsBulk RNA-Seq of Drosophila melanogaster heads after neuronal Wwox knockdown and AB42 overexpression versus control
Wwox knockdown in Drosophila melanogaster neurons (elav-GAL4) also expressing human AB42 worsens lifespan and climbing as well as increasing AB42 load. To understand these effects further we performed transcriptomics on the same genotypes. Neurons expressing RNAi Control and a LacZ control, RNAi Con...
ORGANISM(S): Drosophila melanogaster 
2025-04-18 | E-MTAB-14948 | biostudies-arrayexpress
TranscriptomicsBulk RNA-Seq of Drosophila melanogaster heads after neuronal Wwox and AB42 overexpression versus control
Neuronal Wwox overexpression using CRISPRa in Drosophila melanogaster also expressing human AB42 can rescue amyloid related phenotypes. To understand how this may occur we performed bulk transcriptomics on day 14 heads from the same genotypes: 1) Control gRNA + lacZ expression control, 2) Control gR...
ORGANISM(S): Drosophila melanogaster 
2025-04-18 | E-MTAB-14949 | biostudies-arrayexpress
TranscriptomicsBulk RNA-Seq of Drosophila melanogaster heads after sl knockdown in glia versus control
In a genetic screen we identified that glial knockdown of small wing (sl) impacts engulfment of dying neurons. To understand the roles of glial sl further, we performed bulk transcriptomics. Here we extracted RNA from pooled Drosophila heads after sl knockdown using the repo-GAL4 driver and compared...
ORGANISM(S): Drosophila melanogaster 
2024-06-01 | E-MTAB-14080 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Drosophila melanogaster Cdk12-null mutants versus control
In a forward genetic screen, we have previously identified a null mutant of Cdk12 that results in alterations in actin dynamics, the axon initial segment and electrophysiology in Drosophila melanogaster. To decipher how Cdk12 may be having these effects, we extracted RNA from pooled Drosophila heads...
ORGANISM(S): Drosophila melanogaster 
2023-01-01 | E-MTAB-12090 | biostudies-arrayexpress
MetabolomicsThe timing of bacterial mesophyll infection shapes the leaf chemical landscape during the interaction

Chemistry in eukaryotic intercellular spaces is shaped by both hosts and symbiotic microorganisms such as bacteria. Pathogenic microorganisms like barley associated Xanthomonas translucens (Xt) swiftly overtake the inner leaf tissue becoming the dominant microbial community member during disease ...

2024-02-01 | MTBLS7676 | MetaboLights
TranscriptomicsRibosomal Protein Gene Deletions in Diamond Blackfan Anemia
Diamond Blackfan anemia is a congenital bone marrow failure syndrome characterized by hypoproliferative anemia, often with associated physical abnormalities. Perturbations of the ribosome appear critically important to the development of DBA, as alterations in 9 different ribosomal protein genes ha...
ORGANISM(S): Homo sapiens 
2012-01-15 | E-GEOD-31575 | biostudies-arrayexpress
UnknownViews and Experiences of Travelers from US States to Zika-Affected Areas.
Not available
S-EPMC11308926 | biostudies-literature
UnknownDistinct impacts of sodium channel blockers on the strength-duration properties of human motor cortex neurons.
Not available
S-EPMC12284445 | biostudies-literature
MetabolomicsMetabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides
European common ash, Fraxinus excelsior L., is currently threatened by Ash dieback (ADB) caused by the fungus, Hymenoscyphus fraxineus. To detect and identify metabolites that may be products of pathways important in contributing to resistance against H. fraxineus we performed untargeted metabolomic...
2016-11-09 | MTBLS372 | MetaboLights
GenomicsWhole-genome nucleosome mapping in meiotic diploid S. cerevisiae
We determined nucleosome positions throughout the genome in diploid S. cerevisiae undergoing early stages of synchronous meiosis. This study sought to assess if systematic reorganization of nucleosomes occurs during meiotic prophase at or near sites of DNA double strand break formation. Six samples ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-07 | E-GEOD-26452 | biostudies-arrayexpress
Sort   by:  
 Page size