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MetabolomicsMetabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study)

Diatoms perform about 20% of photosynthesis on earth, play a crucial role in forming the base of the marine food web, and sequester anthropogenic carbon into the deep ocean through the biological pump. In some areas of the ocean, diatom growth is limited by the organic micronutrient cobalamin (vi...

2019-06-04 | MTBLS703 | MetaboLights
MetabolomicsMetabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study)

Diatoms perform about 20% of photosynthesis on earth, play a crucial role in forming the base of the marine food web, and sequester anthropogenic carbon into the deep ocean through the biological pump. In some areas of the ocean, diatom growth is limited by the organic micronutrient cobalamin (vi...

2019-06-04 | MTBLS708 | MetaboLights
ModelsTan2012 - Antibiotic Treatment, Inoculum Effect
Tan2012 - Antibiotic Treatment, Inoculum Effect The efficacy of many antibiotics decreases with increasing bacterial density, a phenomenon called the ‘inoculum effect’ (IE). This study reveals that, for ribosome-targeting antibiotics, IE is due to bistable inhibition of bacterial g...
2024-09-02 | BIOMD0000000425 | BioModels
UnknownEvaluating a novel model of hepatitis B care, Hep B PAST, in the Northern Territory of Australia: results from a prospective, population-based study.
Not available
S-EPMC11222935 | biostudies-literature
UnknownA program to respond to otitis media in remote Australian Aboriginal communities: a qualitative investigation of parent perspectives.
Not available
S-EPMC5840719 | biostudies-literature
TranscriptomicsGuselkumab (interleukin-23-specific monoclonal antibody) demonstrates clinical and molecular response in moderate-to-severe psoriasis
A gene expression profiling study was conducted in which skin biopsy samples were collected for RNA extraction and hybridization to microarrays from patients with moderate-to-severe psoriasis who participated in the phase 1, guselkumab first-in-human randomized, double-blind, placebo-controlled tria...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-51440 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Expression in Daphnia magna Suggests Distinct Modes of Action and Bioavailability for ZnO nanoparticles and Zn ions
Zinc Oxide nanoparticles (ZnO NPs) are being rapidly developed for use in consumer products, wastewater treatment and chemotherapy providing several possible routes for ZnO NP exposure to humans and aquatic organisms. Recent studies have shown that ZnO NPs undergo rapid dissolution to Zn+2, but the...
ORGANISM(S): Daphnia magna 
2010-12-31 | E-GEOD-22051 | biostudies-arrayexpress
UnknownSafe and transparent introduction and evaluation of targeted axillary dissection in patients with node-positive breast cancer undergoing primary surgery: international consensus process.
Not available
S-EPMC12574671 | biostudies-literature
TranscriptomicsRNA-Seq of Single Prostate CTCs Implicates Non-Canonical Wnt Signaling in Antiandrogen Resistance
Prostate cancer is initially responsive to androgen deprivation, but the effectiveness of androgen receptor (AR) inhibitors in recurrent disease is variable. Biopsy of bone metastases is challenging, hence sampling circulating tumor cells (CTCs) may reveal drug resistance mechanisms. We established ...
ORGANISM(S): Homo sapiens 
2015-09-17 | E-GEOD-67980 | biostudies-arrayexpress
GenomicsGenetic Heterogeneity of Diffuse Large B Cell Lymphoma

We sequenced exomes of 94 DLBCL tumors and cell lines. 34 of the tumors had paired normal tissue. Our work elucidates commonly occurring gene-coding mutations in DLBCL.

phs000573.v1.p1 | EGA
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