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MetabolomicsSPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids
Characterization of endogenous metabolites and xenobiotics is essential to deconvoluting the genetic and environmental causes of disease. However, surveillance of chemical exposure and disease-related changes in large cohorts requires an analytical platform that offers rapid measurement, high sensit...
2017-02-14 | MTBLS427 | MetaboLights
ProteomicsMulti-Omic Evidence of Brain Region Specific APOE Genotype Perturbations in Alzheimer's Disease
Simultaneous extraction of proteins and lipids from human frontal cortex and cerebellum brain tissue was performed using the MPLEx procedure for both control and Alzheimer's disease patients. The isolated proteins were then reduced, alkylated, tryptically digested and evaluated with LC-IMS-MS. The p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-08 | MSV000092627 | MassIVE
ProteomicsFrom plants to ants: Evaluating lipidomic changes in leaf-cutter ant fungus gardens
Leaf-cutter ants use fresh plant material to cultivate an obligate mutualistic fungus Leucoagaricus gongylophorus in specialized fungus gardens to access and transform nutrients from plant biomass that would otherwise be unavailable to the ants. Here, we evaluated the lipidomic differences between t...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2019-10-30 | MSV000084520 | MassIVE
ProteomicsRaw data for the characterization of a Pseudomonas putida malonyl-ACP decarboxylase
Raw data for top down LCMS for detecting modifications on recombinant proteins, and GCMS for fatty acid methyl ester analysis. Sample nomenclature is summarized in the Powerpoint and PDF files. Details of experiments are given in the associated manuscript.
ORGANISM(S): Pseudomonas Putida Kt2440 (ncbitaxon:160488) 
MSV000090294 | MassIVE
MetabolomicsGNPS - From plants to ants: Evaluating lipidomic changes in leaf-cutter ant fungus gardens
Leaf-cutter ants use fresh plant material to cultivate an obligate mutualistic fungus Leucoagaricus gongylophorus in specialized fungus gardens to access and transform nutrients from plant biomass that would otherwise be unavailable to the ants. Here, we evaluated the lipidomic differences between t...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2019-10-30 | MSV000084520 | GNPS
ProteomicsSoil metaproteomics data analysis based on de novo sequencing with the deep learning-based Kaiko model
We generated a protein database directly from soil metaproteomic data by identifying the microbial composition using the Kaiko model's de novo sequencing methods. We first analyzed the mass spectra de novo (without a database), identifying species from the observed peptides. We next gathered full p...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2020-10-20 | MSV000086336 | MassIVE
ProteomicsCalu-3 cell proteome response to H1N1 virus
Proteomics data from cell culture; Treated with wild-type H1N1 and mockulum; 5 biological replicates
ORGANISM(S): Influenza A Virus (a/wilson-smith/1933(h1n1)) (ncbitaxon:381518) Homo Sapiens (ncbitaxon:9606) 
2016-08-04 | MSV000080026 | MassIVE
ProteomicsMetagenomic and metaproteomic insights into bacterial communities in leaf-cutter ant fungus gardens
Instrument data for publication "Metagenomic and metaproteomic insights into bacterial communities in leaf-cutter ant fungus gardens", ISME J. 2012 Sep; 6(9): 1688-1701. PMID: 22378535. PMCID: PMC3498920
ORGANISM(S): Environmental Samples <verrucomicrobiales> (ncbitaxon:48468) 
2018-05-25 | MSV000082408 | MassIVE
TranscriptomicsMetabolic Reprogramming During Purine Stress in the Protozoan Pathogen Leishmania donovani
The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to environmental changes, such as nutrient availability....
ORGANISM(S): Leishmania donovani 
2014-02-01 | E-GEOD-48394 | biostudies-arrayexpress
MetabolomicsGNPS - Multi-Omic Evidence of Brain Region Specific APOE Genotype Perturbations in Alzheimer's Disease
Simultaneous extraction of proteins and lipids from human frontal cortex and cerebellum brain tissue was performed using the MPLEx procedure for both control and Alzheimer's disease patients. The isolated proteins were then reduced, alkylated, tryptically digested and evaluated with LC-IMS-MS. The p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-08 | MSV000092627 | GNPS
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