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TranscriptomicsMetabolic switches and adaptations deduced from the proteomes of Streptomyces coelicolor wild type and phoP mutant grown in batch culture
Bacteria in the genus Streptomyces are soil dwelling oligotrophs and important producers of secondary metabolites. Previously we showed that global mRNA expression was subject to a series of metabolic and regulatory switches during the life time of a fermentor batch culture of S. coelicolor M145. He...
ORGANISM(S): Streptomyces coelicolor 
2011-12-31 | E-GEOD-31068 | biostudies-arrayexpress
MetabolomicsContribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fun...
2022-01-14 | MTBLS1679 | MetaboLights
UnknownOutcome after reduced chemotherapy for intermediate-risk neuroblastoma.
Not available
S-EPMC2993160 | biostudies-literature
GenomicsNext Generation Mendelian Genetics: Kabuki Syndrome

The ultimate purpose of this research is to identify genes causing hereditary disorders. We are scaling a new approach to identify the candidate genes and gene mutations that underlie rare human Mendelian (a set of primary tenets relating to the transmission of hereditary characteristics from...

phs000295.v1.p1 | EGA
UnknownSensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.
Not available
S-EPMC8274402 | biostudies-literature
UnknownCirculating tumor cell number and endocrine therapy index in ER positive metastatic breast cancer patients.
Not available
S-EPMC8196036 | biostudies-literature
UnknownMiddle-childhood executive functioning mediates associations between early-childhood autism symptoms and adolescent mental health, academic and functional outcomes in autistic children.
Not available
S-EPMC9291328 | biostudies-literature
UnknownDiagnostic utility of exome sequencing followed by research reanalysis in human brain malformations.
Not available
S-EPMC10914449 | biostudies-literature
TranscriptomicsMetabolic switching in Streptomyces coelicolor Timeseries 1
Background: During the lifetime of a fermenter culture, the soil bacterium S. coelicolor undergoes a major metabolic switch from exponential growth to antibiotic production. We have studied gene expression patterns during this switch, using a specifically designed Affymetrix genechip and a high-reso...
ORGANISM(S): Streptomyces coelicolor 
2010-05-18 | E-GEOD-18489 | biostudies-arrayexpress
UnknownOsimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.
Not available
S-EPMC6762027 | biostudies-literature
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