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ProteomicsImproved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides
Computational, genomic, and proteomic approaches have been used to discover nonannotated proteincoding small open reading frames (smORFs). Some novel smORFs have crucial biological roles in cells and organisms, which motivates the search for additional smORFs. Proteomic smORF discovery methods are a...
ORGANISM(S): Homo sapiens (Human) 
2017-10-17 | PXD005643 | Pride
Smorf-encoded polypeptides (seps) Lc-ms 
ProteomicsImproved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides
Computational, genomic, and proteomic approaches have been used to discover nonannotated proteincoding small open reading frames (smORFs). Some novel smORFs have crucial biological roles in cells and organisms, which motivates the search for additional smORFs. Proteomic smORF discovery methods are a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-26 | MSV000084014 | MassIVE
ProteomicsLong noncoding RNA (lncRNA), smORF encoded polypeptides (SEPs), NONCODE database, enrichment, mass spectrometry
Many small open reading frames (smORFs) embedded in lncRNA transcripts have been shown to encode biologically functional polypeptides (smORFs-encoded polypeptides, SEPs) in different organisms. Despite significant advances in genomics, bioinformatics and proteomics that largely enabled the discovery...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-06-15 | PXD019486 | Pride
Noncode database Mass spectrometry Long noncoding rna (lncrna) Enrichment Smorf encoded polypeptides (seps) 
ProteomicsDeeply mining a universe of peptides Encoded by Long Noncoding RNAs
Long non-coding RNAs (lncRNAs) are generally defined as RNA transcripts longer than 200 nucleotides that are not translated into proteins. Recently, many small open reading frames (smORFs) embedded in lncRNA scripts have been verified to be able to encode functional polypeptides (namely lncRNA-SEPs ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-05-06 | PXD016981 | Pride
Lncrna Mass spectrometry Smorf Enrichment Seps 
UnknownImproved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides.
Not available
S-EPMC4939623 | biostudies-literature
ProteomicsOptimized MeOH/MTBE-based Protein Precipitation and Lipid Removal Enables High Enrichment of Low Molecular Weight Peptides and Proteins from Human Plasma
Low molecular weight (LMW) peptides and proteins (LMWPs, < 30 kDa) in human plasma, serving as potential biomarkers or drug targets, are endowed with a wealth of biological and clinical research values. However, the extraction of LMW species is retarded by high-abundance proteins (HAPs) and therein ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-07 | PXD016957 | Pride
Human Plasma Lc-ms/ms 
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