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TranscriptomicsHigh-fat diet induced gene expression changes in mouse retina may be prevented by introducing bilberries in diet
Obesity and diabetes associated visual impairment and vascular dysfunctions are increasing reasons for vision loss. The detailed mechanisms in these diseases are still largely unknown, but mice models have been useful to study these mechanisms and explore the detailed effects of potential compounds....
ORGANISM(S): Mus musculus 
2012-09-08 | E-GEOD-34154 | biostudies-arrayexpress
TranscriptomicsAscl1, Nurr1 and Lmx1 convert mouse and human fibroblasts into functional dopaminergic neurons without passing through an intermediate precursor state
Lineage-specific transcription factors, which drive cellular identity during embryogenesis, have been shown to convert cell fate when express ectopically in heterologous cells. Herein, we screened the key molecular factors governing the dopaminergic neuronal specification during brain development fo...
ORGANISM(S): Mus musculus 
2011-07-04 | E-GEOD-27174 | biostudies-arrayexpress
TranscriptomicscDNA Microarray 1: Compression Xylem vs. Opposite Xylem
The within-tree variation in wood properties constitutes an exceptional model to study the mechanisms that adjust the different biosynthetic pathways providing substrates with the massive and variable demands of different biosynthetic reactions of cell wall polymers. Although a few genes have been r...
ORGANISM(S): Pinus pinaster 
2012-05-05 | E-GEOD-37678 | biostudies-arrayexpress
TranscriptomicscDNA Microarray 2: Compression Xylem vs. Opposite Xylem
The within-tree variation in wood properties constitutes an exceptional model to study the mechanisms that adjust the different biosynthetic pathways providing substrates with the massive and variable demands of different biosynthetic reactions of cell wall polymers. Although a few genes have been r...
ORGANISM(S): Pinus pinaster 
2012-05-05 | E-GEOD-37736 | biostudies-arrayexpress
TranscriptomicsA family of secreted pathogenesis-related proteins in Candida albicans
Analyzing culture supernatants of yeast and hyphal cells of Candida albicans by mass spectrometry, we found two close homologues of pathogenesis-related (PR-) 1 proteins, Rbe1p and Rbt4p, in the secretome of this human pathogen. By sequence homology, we assigned three yet not characterized open read...
ORGANISM(S): Candida albicans 
2013-03-25 | E-GEOD-28212 | biostudies-arrayexpress
TranscriptomicsEffect of water removal on Fundulus heteroclitus embryo transcriptome
The changes in the transcriptome of Fundulus heteroclitus embryos incubated in water or in air from the blastula stage was investigated. Embryos at blastula stage were sampled after different times under water or air, and at the same temperature, and compared by using a cDNA microarray containing 15...
ORGANISM(S): Fundulus heteroclitus 
2013-04-15 | E-GEOD-19424 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of skeletal muscle tissue from spontaneously hypertensive rats and normotensive rats in a set of recombinant inbred strains
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2008-04-15 | E-TABM-458 | biostudies-arrayexpress
TranscriptomicsInfluence of 17M-NM-2-estradiol on Gene Expression of Paracoccidioides During Mycelia-to-Yeast Transition
Background: Paracoccidioides is the causative agent of paracoccidioidomycosis, a systemic mycosis endemic to Latin America. Infection is initiated by inhalation of conidia (C) or mycelial (M) fragments, which subsequently differentiate into yeast (Y). Epidemiological studies show a striking predomin...
ORGANISM(S): Paracoccidioides brasiliensis Pb01 
2011-12-14 | E-GEOD-30466 | biostudies-arrayexpress
TranscriptomicsThe effect of Neuroserpin expression upon HeLa cell gene expression
HeLa cells were stably transfected using the Tet-OnM-BM-. Advanced Cell Line system with Wildtype, G392E and Delta Neuroserpin with neuroserpin expression induced with doxycycline. Gene expression was examined in the absence or presence of 2 ug/ml doxycycline. Four cell lines were analysed: Untran...
ORGANISM(S): Homo sapiens 
2013-04-20 | E-GEOD-46230 | biostudies-arrayexpress
TranscriptomicsA Molecular Taxonomy of Urothelial Carcinoma
Even though urothelial cancer (UC) is the fourth common tumor type among males, progress in treatment development has been deficient. Pathological assessment provides the urologists with only a broad classification, complicated by frequent disagreement among pathologist and the co-existence of diffe...
ORGANISM(S): Homo sapiens 
2012-05-23 | E-GEOD-32894 | biostudies-arrayexpress
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