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TranscriptomicsTranscription profiling of ERK1 and ERK2 knockdown in zebrafish embryos at blastula stage
ERK1 and ERK2 MAPKs are intensively studied signaling proteins that are involved in numerous cellular processes and signaling networks. However, their specific functions in embryonic development remain elusive. The upstream activation pathways for ERK1 and ERK2 are considered to be highly similar, a...
ORGANISM(S): Danio rerio 
2008-01-01 | E-MEXP-1163 | biostudies-arrayexpress
TranscriptomicsDepletion of beta1 integrins in triple negative breast cancer cells causes extensive alterations in gene expression profiles
Interactions with the extracellular matrix (ECM) through integrin adhesion receptors provide cancer cells with physical and chemical cues that act in concert with growth factors to support survival and proliferation. Preclinical studies testing beta1 integrin antagonists in (breast) cancer models h...
ORGANISM(S): Mus musculus 
2014-02-11 | E-MTAB-2185 | biostudies-arrayexpress
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