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UnknownA second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome.
Not available
S-EPMC7608102 | biostudies-literature
TranscriptomicsComparative genomic hybridization of cell lines from 9 different cancer tissue of origin types (Breast, Central Nervous System, Colon, Leukemia, Melanoma, Non-Small Cell Lung, Ovarian, Prostate, Renal) from NCI-60 panel
Array comparative genomic hybridization characterization and comparison of cell lines from 9 different cancer tissue of origin types (Breast, Central Nervous System, Colon, Leukemia, Melanoma, Non-Small Cell Lung, Ovarian, Prostate, Renal) from NCI-60 panel.
ORGANISM(S): Homo sapiens 
2005-11-23 | E-TABM-65 | biostudies-arrayexpress
TranscriptomicsDNA profiling of serous ovarian and Fallopian tube carcinomas with array CGH and MLPA
Primary serous ovarian carcinoma (OVCA) and serous Fallopian tube carcinoma (FTC), both belonging to the BRCA-linked tumour spectrum, share many properties and are treated similarly. However, a detailed molecular comparison has been lacking. We hypothesized that comparative genomic studies of serous...
ORGANISM(S): Homo sapiens 
2008-07-08 | E-GEOD-12040 | biostudies-arrayexpress
TranscriptomicsMicroarray-based CGH in human cancer cell lines
This series represents the data set from the paper Assembly of microarrays for genome-wide measurement of DNA copy number appearing in Nat Genet 2001 Nov;29(3):263-4 and it's web supplement. Specimen procurement, labeling, hybridization and imaging protocols from Nat Genet 2001 Nov;29(3):263-...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-16 | biostudies-arrayexpress
MetabolomicsHuman Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
TranscriptomicsGenome position and gene amplification - expressional profiling of methotrexate resistant colonies
We investigated the influence of genome position on propensity to amplify. First, we integrated a mutant form of DHFR into different positions in the human genome, challenged cells with methotrexate and then studied the genomic alterations arising in drug resistant cells. We observed site specific d...
ORGANISM(S): Homo sapiens 
2007-10-08 | E-GEOD-6361 | biostudies-arrayexpress
TranscriptomicsGenetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility.
This study investigates three radiation exposure scenarios in BALB/c and C57BL/6 mice: (1) low dose (LD) group -- four weekly doses of 7.5 cGy, (2) high dose (HD) group -- four weekly doses of 1.8 Gy, (3) unexposed group -- four weekly sham exposures. We then used comparative expression profiles of ...
ORGANISM(S): Mus musculus 
2012-11-01 | E-GEOD-40066 | biostudies-arrayexpress
UnknownGenetic architecture of the acute and persistent immune cell response after radiation exposure.
Not available
S-EPMC10667298 | biostudies-literature
TranscriptomicsDiverse routes to oral cancer differing in genome instability and risk for cervical node metastasis
Clinically evident oral lesions, oral epithelial dysplasia, precede development of oral squamous cell carcinomas (SCC) and are considered to transform to cancer by acquisition of genetic or epigenetic alterations. Here, we show that, +3q24-qter, -8pter-p23.1, +8q12-q24.2 and +20 are early events id...
ORGANISM(S): Homo sapiens 
2011-11-18 | E-GEOD-28407 | biostudies-arrayexpress
UnknownThe effect of ambient ozone exposure on three types of diabetes: a meta-analysis.
Not available
S-EPMC10061724 | biostudies-literature
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