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TranscriptomicsTranscriptomic profiling of BrO, DMGO and GD2 CAR T cells
Diffuse midline glioma (DMG) is a lethal pediatric brain cancer with limited treatment options. We developed a human brainstem organoid model to study H3.3K27M-driven DMG, enabling formation of patient-like tumors with molecular heterogeneity. To characterize this model, we performed a time-course t...
ORGANISM(S): Homo sapiens 
2025-08-28 | E-MTAB-15147 | biostudies-arrayexpress
TranscriptomicsTranscription profiling to compare Nodular lymphocyte predominant Hodgkins lymphoma and T cell/histiocyte rich B cell lymphoma
T-cell/histiocyte rich B cell lymphoma (THRBL) and nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) share some morphological characteristics, including a prominent stromal reaction, but display a markedly different prognosis. To investigate the difference between the stromal reactions of th...
ORGANISM(S): Homo sapiens 
2009-12-18 | E-GEOD-7788 | biostudies-arrayexpress
TranscriptomicsTargeted scRNA-seq and AbSeq of human CAR-T cell infusion product from 28 cancer patients
Immunotherapy using CD19-directed chimeric antigen receptor (CAR)-T cells has shown excellent results for treatment of B-cell leukaemia and lymphoma. To produce CAR-T cells, the patient’s own T cells are isolated from the blood and modified in a laboratory with a genetic vector to express a tumor an...
ORGANISM(S): Homo sapiens 
2023-07-24 | E-MTAB-12407 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of t(11;18)-positive and t(11;18)-negative MALT lymphoma
Comparison of t(11;18)-positive MALT lymphoma to t(11;18)-negative MALT lymphoma, with a special focus on the NF-KB pathway and it's targets 8 t(11;18)-negative and 6 t(11;18)-positive cases of MALT lymphoma, as well as six spleen control samples (1 mix of spleens and 5 singular spleen samples)
ORGANISM(S): Homo sapiens 
2010-11-25 | E-GEOD-25550 | biostudies-arrayexpress
Transcriptomics3' sequencing of activated murine T cells + / - inhibition of arginine methylation
Activation of naive T cells stimulates increased proliferation coupled with a global switch to usage of proximal poly(A) sites. We wanted to investigate how this polyadenylation switch would be impacted by inhibition of arginine methylation. Therefore, we activated naive murine T cells with anti-CD3...
ORGANISM(S): Mus musculus 
2026-10-19 | E-MTAB-14990 | biostudies-arrayexpress
GenomicsTranscriptomic analysis of liver CD8+ T cells
Sorted single CD8+T cells expressing CD14 from human liver for SMARTSeq2. Livers processed: Kucykowicz et al STAR Prot 2022:pubmed.ncbi.nlm.nih.gov/35516846/ Published: Pallett et al Nature 2022 Tissue CD14+CD8+T-cells are reprogrammed by myeloid cells and modulated by LPS The liver is bathed in...
EGAS00001006885 | EGA
TranscriptomicsGlobal transcriptome changes in perennial ryegrass during early infection by pink snow mould
Lack of resistance to pink snow mould (Microdochium nivale) is seen as a major constraint for adaptation of perennial ryegrass (Lolium perenne L.) at higher latitudes. Plants generally become more resistant to snow moulds after cold acclimation, and almost all investigations of genetic variation in ...
ORGANISM(S): Lolium perenne 
2016-04-29 | E-MTAB-4459 | biostudies-arrayexpress
UnknownModelling potential habitat for snow leopards (Panthera uncia) in Ladakh, India.
Not available
S-EPMC6350993 | biostudies-literature
TranscriptomicsTranscription profiling of mouse naive CD8+ T-cell differentiation during a primary immune response
Title: Gene Expression analysis of naive CD8+ T-cell differentiation during a primary immune response Description: C57BL/6 wild type mice are administered GK1.5 (depleting anti CD4 antibody) or isotope control by intraperitoneal injection at 3 and 1 day pre-infection, then every 36-48 hour...
ORGANISM(S): Mus musculus 
2005-09-29 | E-MIMR-38 | biostudies-arrayexpress
UnknownPrey preference of snow leopard (Panthera uncia) in South Gobi, Mongolia.
Not available
S-EPMC3290533 | biostudies-literature
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