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Proteomics,MultiomicsSNW1 is required for sister chromatid cohesion
Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hum...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-02 | MSV000080878 | MassIVE
ProteomicsSNW1 is required for sister chromatid cohesion
Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hum...
ORGANISM(S): Homo sapiens (Human) 
2016-06-29 | PXD001249 | Pride
Pre-mrna splicing Snw1 Mitosis Cell cycle Sister chromatid cohesion 
UnknownSNW1 is a prognostic biomarker in prostate cancer.
Not available
S-EPMC6495565 | biostudies-literature
GenomicsTranscriptome wide identification of retained introns upon depletion of the splicing factors WBP11 or SNW1
Transcriptome wide identification of retained introns upon depletion of the splicing factors WBP11 or SNW1
PRJNA530564 | ENA
UnknownSNW1 promotes lymphatic metastasis in bladder cancer by modulating SRPK1 splicing.
Not available
S-EPMC12907903 | biostudies-literature
UnknownSNW1, a Novel Transcriptional Regulator of the NF-κB Pathway.
Not available
S-EPMC6336138 | biostudies-literature
TranscriptomicsTranscriptome wide identification of retained introns upon depletion of the splicing factors WBP11 or SNW1
We identified introns that are dependent on WBP11 or SNW1 for efficient splicing. WBP11 and SNW1 were depleted by RNAi and compared to a mock transfected population of cells. WBP11 was also depleted by auxin and compared to an untreated population of cells
ORGANISM(S): Homo sapiens 
2019-04-03 | GSE129231 | GEO
UnknownMutations in the spliceosomal gene SNW1 cause neurodevelopment disorders with microcephaly.
Not available
S-EPMC12435841 | biostudies-literature
UnknownInhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells.
Not available
S-EPMC4329010 | biostudies-literature
TranscriptomicsTranscriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8
We identified which mRNAs are dependent on the splicing factors SNW1 or PRPF8. These factors were depleted in HeLa cells by RNAi, and the levels of intronic reads in mRNAs was compared to control RNAi. Intronic reads from polyA containing RNAs from HeLa cells and mSnw1-LAP 'rescued' cells, both depl...
ORGANISM(S): Homo sapiens 
2014-09-04 | E-GEOD-61071 | biostudies-arrayexpress
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