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ProteomicsAutoinhibition of Trio guanine nucleotide exchange factor activity for Rac1 by its spectrin repeats is disrupted by neurodevelopmental disorder-related genetic variants
Crosslinking MS of SR6-GEF1 construct of Human Trio. BS3 crosslinking of wild-type and three point mutants implicated in neurodevelopmental disorders (E883D, R1078Q, D1368V). Data acquired using FAIMS ion mobility source with each sample acquired at 4 different CVs (-40, -50, -60, -70V).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-08 | MSV000089621 | MassIVE
UnknownMolecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Not available
S-EPMC3637702 | biostudies-literature
ProteomicsIdentification of Long Lived Synaptic Proteins by Comprehensive Proteomic Analysis of Synaptosome Protein Turnover
Memory formation is believed result from changes in synapse strength and structure. While memories may persist for the lifetime of an organism, the proteins and lipids that make up synapses undergo constant turnover with lifetimes from minutes to days. The molecular basis for memory maintenance may ...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2018-03-19 | PXD007156 | Pride
Protein turnover Long lived protein Synaptosome 
TranscriptomicsSkeletal muscle of glucocorticoid deprived and treated mice by SAGE
Forty male C57BL6 mice 12-15 weeks old fed chow ad libitum. 30 mice underwent adrenalectomy (Adx) and 10 others a sham-Adx. Three or 24 h before tissue sampling, groups of 10 mice received an I.P. injection of cortisol (0.1 mg per mice), while the remaining Adx and intact mice received an I.P. injec...
ORGANISM(S): Mus musculus 
2005-01-05 | E-GEOD-2122 | biostudies-arrayexpress
GenomicsNon-invasive whole genome sequencing of a human fetus

The overall purpose of this study was to demonstrate the feasibility of producing haplotype-phased whole genome sequence data from a fetus using free fetal DNA isolated from maternal plasma collected during the first half of gestation.

phs000500.v1.p1 | EGA
UnknownAnalysis of ten Brucella genomes reveals evidence for horizontal gene transfer despite a preferred intracellular lifestyle.
Not available
S-EPMC2681906 | biostudies-literature
UnknownSystematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen.
Not available
S-EPMC6800164 | biostudies-literature
UnknownA nuclear branched-chain amino acid catabolism pathway controls histone propionylation in pancreatic cancer.
Not available
S-EPMC12191106 | biostudies-literature
UnknownRegistration-free analysis of diffusion MRI tractography data across subjects through the human lifespan.
Not available
S-EPMC8482444 | biostudies-literature
UnknownInfection-derived lipids elicit an immune deficiency circuit in arthropods.
Not available
S-EPMC5316886 | biostudies-literature
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