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ProteomicsProteomic study of SOAT1 protein targeting compounds in the treatment of liver cancer
Proteomic study of SOAT1 protein targeting compounds in the treatment of liver cancer
ORGANISM(S): Homo Sapiens 
2022-01-11 | PXD030873 |
GenomicsSOAT1 knock-out downregulates the expression of mevalonate pathway genes in PDAC organoids
SOAT1 knock-out downregulates the expression of mevalonate pathway genes in PDAC organoids
PRJNA594605 | ENA
TranscriptomicsSOAT1 knockout enhances sensitivity of liver cancer cells to T cell-based immunotherapy [RNA-seq]
SOAT1 knockout enhances the responsiveness of human liver cancers to T cell-based therapies without significantly impacting tumor proliferation. We aimed to elucidate how SOAT1 knockout influences sensitivity to T cell therapy. We performed bulk RNA-seq analysis on SOAT1-KO and vector-transduced Hep...
ORGANISM(S): Homo sapiens Mus musculus 
2025-12-31 | GSE280148 | GEO
UnknownSOAT1 methylation is associated with coronary heart disease.
Not available
S-EPMC6829990 | biostudies-literature
UnknownSOAT1 regulates cholesterol metabolism to induce EMT in hepatocellular carcinoma.
Not available
S-EPMC11082151 | biostudies-literature
GenomicsSOAT1 knockout enhances sensitivity of liver cancer cells to T cell-based immunotherapy [RNA-seq]
SOAT1 knockout enhances sensitivity of liver cancer cells to T cell-based immunotherapy [RNA-seq]
PRJNA1176550 | ENA
UnknownSOAT1 promotes mevalonate pathway dependency in pancreatic cancer.
Not available
S-EPMC7478739 | biostudies-literature
TranscriptomicsSOAT1 knock-out downregulates the expression of mevalonate pathway genes in PDAC organoids
One of the emerging cancer vulnerabilities is altered metabolism, and several metabolic pathways have been shown to promote pancreatic ductal adenocarcinoma (PDAC). Here we use genetic targeting to delete SOAT1 from murine PDAC metastasis organoids, and use RNA-seq to identify genes differentially r...
ORGANISM(S): Mus musculus 
2020-06-16 | GSE141737 | GEO
UnknownSOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.
Not available
S-EPMC8591064 | biostudies-literature
UnknownSOAT1 missense variant in two cats with sebaceous gland dysplasia.
Not available
S-EPMC10227112 | biostudies-literature
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