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UnknownAntigen-induced oligomerization of the B cell receptor is an early target of Fc gamma RIIB inhibition.
Not available
S-EPMC2931798 | biostudies-literature
UnknownTerminalia Chebula provides protection against dual modes of necroptotic and apoptotic cell death upon death receptor ligation.
Not available
S-EPMC4846877 | biostudies-literature
TranscriptomicsDiscriminant for genotoxic and non-genotoxic carcinogens by differentially expressed gene profiling
The need for an efficient carcinogenicity test prompted this study, in which we used a microarray-based genomics approach, with a short-term in vivo model, in combination with insights from statistical and mechanistic analyses. We performed additional experiments to support the significance of the m...
ORGANISM(S): Rattus norvegicus 
2011-08-10 | E-GEOD-31307 | biostudies-arrayexpress
TranscriptomicsAnti-tumor activity and acquired resistance mechanism of Dovitinib (TKI258) in RET rearranged lung adenocarcinoma
RET rearrangement is a newly identified oncogenic mutation in lung adenocarcinoma (LADC). Activity of dovitinib (TKI258), a potent inhibitor of FGFR, VEGFR, and PDGFR, in RET-rearranged LADC has not been reported. The aims of the study are to explore anti-tumor effects and mechanisms of acquired res...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-69226 | biostudies-arrayexpress
UnknownLong-term safety and efficacy of ravulizumab in patients with paroxysmal nocturnal hemoglobinuria: 2-year results from two pivotal phase 3 studies.
Not available
S-EPMC9546219 | biostudies-literature
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