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ProteomicsXPO1 amplification abrogates the effects of E571K XPO1 mutation in B-cell lymphoma
XPO1 gene encodes exportin 1 (XPO1) that controls the nuclear export of cargo proteins and RNAs. Almost 25% of primary mediastinal B-cell lymphomas (PMBL) and classical Hodgkin lymphomas (cHL) cases harboured a recurrent XPO1 point mutation (NM_003400, chr2:g61718472C>T) resulting in the E571K modif...
ORGANISM(S): Homo sapiens (Human) 
2020-10-01 | PXD016916 | Pride
Ap-ms U2940 Xpo1 Human cells Exportin 1 K1106 primary mediastinal b-cell lymphomal lines Medb1 Q-exactive plus 
TranscriptomicsCyclin K and cyclin D1b are oncogenic in myeloma cells
To study the oncogenic potential of cyclin D1b in the context of mature B cells we generated several cell clones derived from LP-1 MM cell line expressing either cyclin D1b, Myc or cyclin K oncogenes. Transcriptomic analysis allowed us to describe several mechanisms of cyclin D1b- and K-mediated onc...
ORGANISM(S): Homo sapiens 
2010-04-23 | E-GEOD-15497 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of ectopic cyclin D1-expressing myeloma cells compared to their non expressing counterparts
We analyzed gene expression profiles of myeloma cells belonging to the group of bas prognosis RPMI 8226 and LP1 expressing either the GFP protein or a cyclin D1-GFP fusion protein Two cell lines RPMI 8226 and LP1. Two clones from each cell line GFP and cyclin D1-GFP. Four biological replicates indep...
ORGANISM(S): Homo sapiens 
2014-07-23 | E-GEOD-59673 | biostudies-arrayexpress
UnknownVentilation strategies and risk factors for intraoperative respiratory critical events and postoperative pulmonary complications in neonates and small infants: a secondary analysis of the NECTARINE cohort<sup>☆</sup>.
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S-EPMC12597469 | biostudies-literature
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