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TranscriptomicsRegulation of FAS Exon Definition and Apoptosis by the Ewing Sarcoma Protein
The EwingM-bM-^@M-^Ys sarcoma protein EWS belongs to the TET family (FUS/TLS, EWS, TAF15) of RNA and DNA binding proteins, implicated in DNA transcription, pre-mRNA splicing and maintenance of genomic integrity. Translocations of these genes are characteristic of particular neoplasias, including Ewi...
ORGANISM(S): Homo sapiens 
2014-05-21 | E-GEOD-48065 | biostudies-arrayexpress
TranscriptomicsRegulation of NUMB alternative splicing by RBM5, RBM6 and RBM10 controls cancer cell proliferation (CLIP-Seq)
RBM5, a regulator of alternative splicing of apoptotic genes, and its close homologues, RBM6 and RBM10, are RNA binding proteins frequently deleted or mutated in lung cancer. We report that RBM5/6 and RBM10 antagonistically regulate the proliferative capacity of cancer cells and display distinct pos...
ORGANISM(S): Homo sapiens 
2013-12-20 | E-GEOD-48066 | biostudies-arrayexpress
UnknownFast gap-affine pairwise alignment using the wavefront algorithm.
Not available
S-EPMC8355039 | biostudies-literature
TranscriptomicsEnhancers with tissue-specific activity are enriched in intronic regions
We have performed ChIP-seq of H3K27ac and H3K4me3 histone post-translational modifications at three stages during induced neural differentiation (ESCs, neural progenitors and neurons). This data has allowed us to identify candidate enhancer-like signatures in the genome, which we have defined as reg...
ORGANISM(S): Homo sapiens 
2021-06-16 | E-MTAB-10595 | biostudies-arrayexpress
TranscriptomicsHistone modifications along transdifferentiation from B cell to macrophage
Transdifferentiation of BLaER1 B cell into macrophages is an appropriate model to understand how chromatin behaves along a dynamic process. With this purpose, we have performed chromatin immunoprecipitation experiments of two histone modifications associated to active enhancer activity along 4 time ...
ORGANISM(S): Homo sapiens 
2020-05-08 | E-MTAB-9010 | biostudies-arrayexpress
UnknownOptimal gap-affine alignment in O(s) space.
Not available
S-EPMC9940620 | biostudies-literature
UnknownAnchorWave: Sensitive alignment of genomes with high sequence diversity, extensive structural polymorphism, and whole-genome duplication.
Not available
S-EPMC8740769 | biostudies-literature
UnknownThe Retornus-2 study: impact of respiratory muscle training in subacute stroke patients with dysphagia, study protocol of a double-blind randomized controlled trial.
Not available
S-EPMC8229262 | biostudies-literature
UnknownQuickEd: high-performance exact sequence alignment based on bound-and-align.
Not available
S-EPMC11937955 | biostudies-literature
GenomicsEpigenetics profiling of human BLaER1 pre-B cells transdifferentiation into macrophages
BLaER1 is a human B cell precursor leukemia cell line derived from the RCH-ACV cells. These cells are stably infected with a construct that overexpresses the transcription factor C/EBPa fused with the estrogen receptor hormone binding domain (ER) and GFP. Upon induction with beta-estradiol, C/EBP is...
ORGANISM(S): Homo sapiens 
2022-05-31 | E-MTAB-9825 | biostudies-arrayexpress
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