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GenomicWhole Genome Study for De Novo Mutation Rates

Germline mutations are the source of evolution and contribute substantially to many health-related processes. In this study, we use whole genome deep sequencing data from parents-offspring trios to examine the de novo point mutations (DNMs) in the offspring.

We studied correlation between ...

phs001055 | dbGaP
UnknownIs obesity a risk factor for melanoma?
Not available
S-EPMC9944773 | biostudies-literature
UnknownClinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastases.
Not available
S-EPMC4451171 | biostudies-literature
Transcriptomicsangiogenesis course
This is a time course experiment with 4 - 6 slides per time point where all samples were hybridised to time zero. The microarray slides were scanned using a GenePix 4000B Scanner (Axon Instruments, Foster City, CA, USA). The â??SPOTâ?? software package (CSIRO) was used to identify spots and subtrac...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-779 | biostudies-arrayexpress
TranscriptomicsTranscriptional networks controlling the cell cycle (RNA-seq)
Transcription profiling by RNA-seq of Drosophila S2 cells after knock down of strongest cell cycle regulators to map their genome-wide transcriptional targets (155 assays). RNA samples used for this experiment are a subset of the 200 samples used in Affymetrix microarray experiment E-MTAB-453. E-MTA...
ORGANISM(S): Drosophila melanogaster 
2012-11-26 | E-MTAB-1364 | biostudies-arrayexpress
UnknownT Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation.
Not available
S-EPMC7239328 | biostudies-literature
UnknownA genetically distinct pediatric subtype of primary CNS large B-cell lymphoma is associated with favorable clinical outcome.
Not available
S-EPMC9131901 | biostudies-literature
TranscriptomicsTranscript profiling in S2 cells and salivary glands.
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8297 | biostudies-arrayexpress
TranscriptomicsTo identify and study the regulation of cellulosic enzymes in a biomass degrading gut fungal isolate from horse (Piromyces sp. finn)
Here, we develop a systems-level approach leveraging powerful next generation sequencing, proteomics and phenotypic studies to rapidly obtain an integrated view of lignocellulose degradation in the earliest free living fungi RNA-seq of Piromyces grown on Glucose, Cellulose, Cellulobiose, Avicel, Fil...
ORGANISM(S): Piromyces sp. Finn 
2016-02-12 | E-GEOD-64834 | biostudies-arrayexpress
ProteomicsCytosolic proteome of Staphylococcus aureus HG001 post internalization in bronchial epithelial cells - human dataset
The data set consists of 32 cytosolic samples of human bronchial epithelial cells that were collected during infection with S. aureus. The data include 8 (0h, 1h, 2.5 h, 6.5 h, 24 h, 48 h, 72 h, and 96 h post infection) time points that were collected out of four biological replicates. DIA data and ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082923 | MassIVE
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