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TranscriptomicsscRNA-seq of human somitoids that periodically form somite-like structures
Single-cell RNA sequencing (10X) analyses of human somitoids, novel organoids that periodically form somite-like structures from human iPS cells. Somitoids made with and without Matrigel were compared. Somitoids treated with different concentrations of CHIR (WNT signaling activator) during the initi...
ORGANISM(S): Homo sapiens 
2022-04-07 | E-MTAB-11334 | biostudies-arrayexpress
ProteomicsP300 proximity labeling in human somitoids
This dataset presents the results of proximity-dependent biotinylation targeting the transcriptional coactivator p300 in human somitoids. We endogenously tagged p300 with the biotin ligase miniTurboID in iPSCs, to enable labeling of proximal proteins and thus proteins locatd at enhancers. hiPSCs wer...
ORGANISM(S): Homo sapiens (Human) 
2026-08-07 | PXD070251 | Pride
GenomicsscRNA-seq of human somitoids that periodically form somite-like structures
scRNA-seq of human somitoids that periodically form somite-like structures
PRJEB49868 | ENA
UnknownRegeneration of the human segmentation clock in somitoids in vitro.
Not available
S-EPMC9713707 | biostudies-literature
ProteomicsFrom stem cells to somites: revealing genetic and exogenous factors of human embryogenesis
In this project, we characterized the temporal dynamics of protein expression during the differentiation of human iPSCs to somitoids, stem cell–derived 3D models that recapitulate early embryonic somitogenesis. Using quantitative time-course proteomics, we captured how protein abundance changed as p...
ORGANISM(S): Homo sapiens (Human) 
2026-08-07 | PXD079129 | Pride
Matrigel Ipscs Human somitoids Proteomics Somitogenesis 
UnknownNOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids.
Not available
S-EPMC12404203 | biostudies-literature
GenomicsHuman Somitoids Generated by Reprogramming Pax8+ Urine Cells
Human Somitoids Generated by Reprogramming Pax8+ Urine Cells
PRJNA750787 | ENA
GenomicsHuman Somitoids Generated by Reprogramming Pax8+ Urine Cells [RNA-seq]
Human Somitoids Generated by Reprogramming Pax8+ Urine Cells [RNA-seq]
PRJNA751619 | ENA
GenomicsHuman Somitoids Generated by Reprogramming Pax8+ Urine Cells [scRNA-seq]
Human Somitoids Generated by Reprogramming Pax8+ Urine Cells [scRNA-seq]
PRJNA750727 | ENA
GenomicsHuman Somitoids Generated by Reprogramming Pax8+ Urine Cells [ChIP-seq]
Human Somitoids Generated by Reprogramming Pax8+ Urine Cells [ChIP-seq]
PRJNA750788 | ENA
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