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TranscriptomicsRNA-Seq after knockdown of SON in human embryonic stem cells
Human embryonic stem cells (hESCs) harbor the ability to undergo lineage-specific differentiation into clinically relevant cell types. Transcription factors and epigenetic modifiers are known to play important roles in the maintenance of pluripotency of hESCs. However, little is known about regulati...
ORGANISM(S): Homo sapiens 
2013-08-29 | E-MTAB-1687 | biostudies-arrayexpress
TranscriptomicsDeep transcriptome analysis of mouse embryonic fibroblast following simultaneous overexpression of Stella, Oct4 and Nanos2 (SON)
We constructed a polycistronic lentiviral vector to overexpress 3 germ cell specific genes (Stella, Oct4 and Nanos2) in mouse embryonic fibroblast (MEFs) and evaluated the transcriptome portrait in partially reprogrammed cells.We sequenced RNA samples from bulk cell population of two biological dup...
ORGANISM(S): Mus musculus 
2016-07-30 | E-GEOD-77351 | biostudies-arrayexpress
TranscriptomicsSon Maintains Accurate Splicing of Pre-mRNAs Encoding Chromatin Modifiers
Exon and expression analysis of HeLa cells after knockdown of SON Serine-arginine-rich (SR) proteins play a key role in alternative pre-mRNA splicing in eukaryotes. Our laboratory recently showed that a large SR protein called Son has unique repeat motifs that are essential for maintaining the subnu...
ORGANISM(S): Homo sapiens 
2011-12-22 | E-GEOD-28672 | biostudies-arrayexpress
TranscriptomicsSSH-PCR dehydrated supraoptic nucleus
The magnocellullar neurons (MCNs) of the supraoptic nucleus (SON) of the hypothalamus are the principle source of the neuropeptide hormone vasopressin (VP), which has a crucial role in osmoregulation. Physiological activation of the SON by dehydration results is a massive release of VP from stores i...
ORGANISM(S): Rattus norvegicus 
2010-06-30 | E-GEOD-3132 | biostudies-arrayexpress
TranscriptomicsExpression data from HeLa cells transiently transfected with control siRNA or SON siRNA
SON is a large Ser/Arg (SR)-related protein localized in nuclear speckles. SON siRNA causes defects in mitotic progression and genome instability. We used microarrays to detail the pattern of gene expression after SON knockdown. HeLa cells were grown in 100 mm dishes and transfected with negative co...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-26888 | biostudies-arrayexpress
GenomicsMae Hong Son Ethnic Fermented Foods
Mae Hong Son Ethnic Fermented Foods Metagenome
PRJNA747069 | ENA
GenomicsSon KD in mouse embryonic stem cells
Son KD in mouse embryonic stem cells
PRJNA1128624 | ENA
UnknownNew records and an updated checklist of snakes from Son La Province, Vietnam.
Not available
S-EPMC7314865 | biostudies-literature
ProteomicsSON and SRRM2 form nuclear speckles in human cells
The nucleus of higher eukaryotes is a highly compartmentalized and dynamic organelle consisting of several biological condensates that regulate gene expression at multiple levels. First reported more than 100 years ago by Ramón y Cajal, nuclear speckles (NS) are among the most prominent of such cond...
ORGANISM(S): Homo sapiens (Human) 
2020-10-26 | PXD021814 | Pride
Srrm2  nuclear speckles 
ProteomicsPeptidomics analysis of dromedary camel supraoptic nucleus by tandem mass spectrometry
Peptides were qualitatively characterized in supraoptic nuclei (SON)of dromedary camels by liquid chromatography-mass spectrometry/mass spectrometry. Samples collected in winter and summer were analyzed separately. Qualitative seasonal differences were noted. The presence of the PMCH hormone by dete...
ORGANISM(S): Camelus dromedarius (Dromedary) (Arabian camel) 
2019-11-11 | PXD013869 | Pride
Peptidomics Dehydration Supraoptic nucleus (son) 
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