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ProteomicsSRRM2 wt and SRRM2 S1444P interactome
Multisystem proteinopathy (MSP) is a pleiotropic degenerative disorder which affects the nervous system, muscles, and bones. The identification of risk factors and their molecular contribution to MSP expands our understanding of disease mechanisms. Here, we describe a family with dominantly inherite...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD068260 | Pride
Nuclear speckle Srrm2 Interactome 
ProteomicsSON and SRRM2 form nuclear speckles in human cells
The nucleus of higher eukaryotes is a highly compartmentalized and dynamic organelle consisting of several biological condensates that regulate gene expression at multiple levels. First reported more than 100 years ago by Ramón y Cajal, nuclear speckles (NS) are among the most prominent of such cond...
ORGANISM(S): Homo sapiens (Human) 
2020-10-26 | PXD021814 | Pride
Srrm2  nuclear speckles 
GenomicsSRRM2 Phase Separation Drives Assembly of Nuclear Speckle Subcompartments
SRRM2 Phase Separation Drives Assembly of Nuclear Speckle Subcompartments
PRJNA1015249 | ENA
GenomicsSRRM2 splicing factor modulates cell fate in early development [scRNA-Seq]
SRRM2 splicing factor modulates cell fate in early development [scRNA-Seq]
PRJNA1018486 | ENA
TranscriptomicsT cell Activation is Regulated by Assembly of an RNA-binding Interactome Centered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [total RNA-array]
T cell activation leads to dramatic changes in cellular phenotype. We used CD3/CD28-activated human CD4 T cells to study how RNA binding proteins define the post-transcriptional landscape. Using RIPseq, we identified the RNA interactome of U2AF2 and show at the global level that U2AF2 binds the maj...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-62921 | biostudies-arrayexpress
GenomicsSRRM2 splicing factor modulates cell fate in early development [RNA-Seq]
SRRM2 splicing factor modulates cell fate in early development [RNA-Seq]
PRJNA1018487 | ENA
UnknownSRRM2 organizes splicing condensates to regulate alternative splicing.
Not available
S-EPMC9410892 | biostudies-literature
GenomicsSRRM2 splicing factor modulates cell fate in early development [RNA-Seq 2]
SRRM2 splicing factor modulates cell fate in early development [RNA-Seq 2]
PRJNA1018492 | ENA
GenomicsAlternative splicing analysis of SRRM1 or SRRM2 targets in THP-1 cells
Alternative splicing analysis of SRRM1 or SRRM2 targets in THP-1 cells
PRJNA821233 | ENA
UnknownSRRM2 splicing factor modulates cell fate in early development.
Not available
S-EPMC11070786 | biostudies-literature
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