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ProteomicsGlobal proteomics to study silica nanoparticle-induced cytotoxicity and its mechanisms in HepG2 cells
Silica nanoparticles (SiO2 NPs) are commonly used in medical and pharmaceutical fields. Research into the cytotoxicity and overall proteomic changes occurring during initial exposure to SiO2 NPs is limited. We investigated the mechanism of toxicity in human liver cells according to exposure time [0,...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024206 | Pride
Silica nanoparticles  cytotoxicity  label-free quantification  proteomic analysis  mass spectrometry 
ProteomicsSpatial Multi-Omics Reveals Region-Specific Molecular Signatures in a 6-OHDA Model of Parkinson’s Disease
Parkinson’s disease (PD) is characterized by complex molecular and circuit-level alterations that extend beyond dopaminergic neurodegeneration, yet the spatial integration of metabolic and proteomic changes remains insufficiently explored. Here, we combined time-of-flight secondary ion mass spectrom...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-28 | PXD071834 | Pride
UnknownElectrocardiographic biomarker based on machine learning for detecting overt hyperthyroidism.
Not available
S-EPMC9707932 | biostudies-literature
UnknownTargeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration.
Not available
S-EPMC8602547 | biostudies-literature
UnknownN-methyl-D-aspartate receptors induce M1 polarization of macrophages: Feasibility of targeted imaging in inflammatory response in vivo.
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S-EPMC10064586 | biostudies-literature
UnknownTreat-to-target versus high-intensity statin treatment in patients with or without diabetes mellitus: a pre-specified analysis from the LODESTAR trial.
Not available
S-EPMC10520306 | biostudies-literature
UnknownHuman NTCP in complex with YN69083 Fab
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EMPIAR-11178 | biostudies-other
UnknownLong-Term Survival Outcomes of Elderly Patients Treated With S-1 or Capecitabine Plus Oxaliplatin for Stage II or III Gastric Cancer: A Multicenter Cohort Study.
Not available
S-EPMC8980600 | biostudies-literature
UnknownArtificial Intelligence-Driven Drafting of Chest X-Ray Reports: 2025 Position Statement From the Korean Society of Thoracic Radiology Based on an Expert Survey.
Not available
S-EPMC12568761 | biostudies-literature
UnknownStructural insights into the HBV receptor and bile acid transporter NTCP.
Not available
S-EPMC9242859 | biostudies-literature
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