Sort   by:  
 Page size 
ProteomicsPrimary mouse embryonic palatal mesenchyme LC-MS/MS
To identify proteins phosphorylated by Akt downstream of PI3K-mediated PDGFRalpha signaling, we immunoprecipitated Akt phosphorylation substrates from PDGF-AA-treated primary mouse embryonic palatal mesenchyme (MEPM) lysates and analyzed the peptides by nano LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2019-06-04 | PXD000779 | Pride
Mouse Primary embryonic palatal mesenchyme Lc-ms/ms 
TranscriptomicsIdentification of immediate early transcriptional targets of ephrin-B1 forward signaling
The goal of this study was to identify immediate early transcriptional targets of ephrin-B1 forward signaling that are relevant to palatogenesis. The Ephs compose a family of receptor tyrosine kinase signaling molecules that can be activated by their cognate ligands, the ephrins. Despite the import...
ORGANISM(S): Mus musculus 
2010-09-20 | E-GEOD-23539 | biostudies-arrayexpress
ProteomicsDiverse Fgfr1 signaling pathways and endocytic trafficking regulate early mesoderm development
The Fibroblast growth factor (FGF) pathway is a conserved signaling pathway required for embryonic development. Activated FGF receptor 1 (FGFR1) drives multiple intracellular signaling cascade pathways, including ERK/MAPK and PI3K/AKT, collectively termed canonical signaling. However, unlike Fgfr1 n...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD050632 | Pride
Fgf  mesoderm development  kidney development  cell signaling  cell adhesion  endocytic trafficking 
GenomicsClonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen
Somatic transposon mutagenesis in mice is an efficient strategy to investigate the genetic mechanisms of tumorigenesis. The identification of tumor driving transposon insertions traditionally requires the generation of large tumor cohorts to obtain information about common insertion sites. Tumor dri...
ORGANISM(S): Mus musculus 
2013-08-28 | E-GEOD-46210 | biostudies-arrayexpress
TranscriptomicsExpression data from newborn mouse brain expressing a constitutively active PDGFRb
To identify targets of PDGFRb signaling and potentially new markers for pericyte activation, we used microarray analysis to compare gene expression in control and mutant pericytes expressing a constitutively active PDGFRb. We chose 1 day after birth as a time point for analysis because the number of...
ORGANISM(S): Mus musculus 
2011-06-15 | E-GEOD-29284 | biostudies-arrayexpress
Sort   by:  
 Page size