Sort   by:  
 Page size 
TranscriptomicsListeria monocytogenes SOS response determined after mitomycin C exposure
The SOS response is a conserved pathway that is activated under certain stress conditions and is regulated by the repressor LexA and the activator RecA. The food-borne pathogen Listeria monocytogenes contains RecA and LexA homologs, but their roles in Listeria have not been established. In this stud...
ORGANISM(S): Listeria monocytogenes EGD-e 
2010-05-19 | E-GEOD-12634 | biostudies-arrayexpress
TranscriptomicsHuman subcutaneous adipose tissue gene expression (SOS Sib-pair study, offspring cohort)
Obesity has considerable effects on morbidity and mortality, and the prevalence of obesity has been increasing rapidly worldwide during the past two decades. Even if obesity affects the entire individual, adipose tissue plays a central role in the development of obesity. Expression profiling of adip...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-27916 | biostudies-arrayexpress
ProteomicsMechanistic Divergence Between SOS Response Activation and Antibiotic-Induced Plasmid Conjugation in E. coli
Project description: Plasmids, frequently carried by environmental and pathogenic bacteria, play a critical role in rapid dissemination of antibiotic resistance through conjugation. The use of antibiot-ics further induces this conjugative transmission between bacteria and thereby plays a role in the...
ORGANISM(S): Escherichia coli 
2025-05-08 | PXD063721 | Pride
Sos response  conjugation  antibiotics  e. coli  inci1 
ModelsShimoni2009 - Escherichia Coli SOS
Shimoni2009 - Escherichia Coli SOS Simple model, involving only the basic components of the circuit, sufficient to explain the peaks in the promoter activities of recA and lexA. This model is described in the article: Stochastic...
2005-01-01 | MODEL2937159804 | BioModels
ProteomicsA Sos Proteomimetic as a Pan-Ras Inhibitor
Aberrant Ras signaling is linked to a wide spectrum of hyperproliferative diseases, and components of the signaling pathway, including Ras, have been the subject of intense and ongoing drug discovery efforts. The cellular activity of Ras is modulated by its association with the guanine nucleotide ex...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-02 | MSV000086972 | MassIVE
TranscriptomicsControl of the E. coli SOS regulon expression by intracellular dNTP pool changes
We studied SOS mutator effect mediated by recA730 and changes in the dNTP pool. We found that established dNTP pool changes resulting from deficiencies in the ndk or dcd genes, had a strongly suppressive effect on the recA730 mutator effect. To investigate whether the observed reduction in SOS muta...
ORGANISM(S): Escherichia coli 
2015-03-31 | E-GEOD-62898 | biostudies-arrayexpress
TranscriptomicsMEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma (SCC)
Genomic analyses of SCC have yet to yield significant strategies against pathway activation to improve treatment. Platinum-based chemotherapy remains the mainstay of treatment for SCC of different histotypes either as a single agent or alongside other chemotherapeutic drugs or radiotherapy; however,...
ORGANISM(S): Homo sapiens 
2015-08-05 | E-GEOD-66549 | biostudies-arrayexpress
GenomicsRumex salicifolius isolate:RUSA-SOS-NV030-372-10
Rumex salicifolius isolate:RUSA-SOS-NV030-372-10 Genome sequencing
PRJNA1070717 | ENA
TranscriptomicsDpiA overexpression
The dpiA and dpiB genes of Escherichia coli, which are orthologs of genes that regulate citrate uptake and utilization in Klebsiella pneumoniae, comprise a two-component signal transduction system that can modulate the replication of and destabilize the inheritance of pSC101 and certain other plasmi...
ORGANISM(S): Escherichia coli 
2006-01-30 | E-GEOD-4112 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Escherichia coli overexpressing dpiA vs wt
The dpiA and dpiB genes of Escherichia coli, which are orthologs of genes that regulate citrate uptake and utilization in Klebsiella pneumoniae, comprise a two-component signal transduction system that can modulate the replication of and destabilize the inheritance of pSC101 and certain other plasmi...
ORGANISM(S): Escherichia coli 
2005-12-06 | E-SMDB-3557 | biostudies-arrayexpress
Sort   by:  
 Page size