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TranscriptomicsProfiling by array of human Glioblastoma multiforme (GBM) tumor samples to asses the intra-tumoral heterogeneity in genomic copy number aberrations
Glioblastoma multiforme (GBM) is a highly heterogeneous disease that shows an wide range of genetic abnormalities in comparison to other astrocytic tumors. We have extracted between 4 and 8 tumor subsamples from different areas of the malignant tissue that were at least 1cm apart. Our aim to asses t...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-MTAB-1215 | biostudies-arrayexpress
GenomicsBreast cancer multi-region sequencing from Sottoriva Lab
Data Access Committee EGAC00001000890
EGAC00001000890 | EGA
GenomicsColorectal cancer BB sequencing
We performed whole-exome sequencing of tumour bulks from opposite side of the neoplasm (A/B). From each we selected a panel of sub-clonal mutations and profiled multiple single tumour glands from the same neoplasm using high depth targeted re-sequencing. The aim was to infer tumour evolutionary dyna...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-MTAB-2247 | biostudies-arrayexpress
TranscriptomicsColorectal cancer BB copy number arrays
We performed the sampling of multiple single tumour glands from 8 colorectal carcinomas and 3 adenomas with the aim of inferring tumour evolutionary dynamics and reconstruct the timeline of progression
ORGANISM(S): Homo sapiens 
2014-12-22 | E-MTAB-2140 | biostudies-arrayexpress
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