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ProteomicsRepurposing E3 ubiquitin ligases as cell surface protein degraders using Proteolysis Targeting Antibodies
The majority of current therapeutics targeting plasma membrane receptors function by antagonizing ligand binding or enzymatic activities. Typical mammalian proteins, however, consist of multiple domains executing discrete but coordinated activities, and saturating inhibition of one functional domain...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-25 | MSV000089542 | MassIVE
UnknownRisk Variants in Three Alzheimer's Disease Genes Show Association with EEG Endophenotypes.
Not available
S-EPMC8075394 | biostudies-literature
UnknownMetabolic Profiling at COVID-19 Onset Shows Disease Severity and Sex-Specific Dysregulation.
Not available
S-EPMC9280146 | biostudies-literature
TranscriptomicsAnalysis of microRNA proflie of peripheral blood mononuclear cells (PBMCs) in HIV-1 infected patients under different clinical status respect to hepatitis C virus (HCV) infection.
A total of 117 HIV-1 infected patients were analyzed. These individuals were categorized in three different groups according to their infectious status for HCV: A) HIV+/HCV+ group, (n=45) patients with HIV infection and active HCV-chronic infection naïve to any HCV treatment (positive PCR and positi...
ORGANISM(S): Homo sapiens 
2021-11-23 | E-MTAB-8274 | biostudies-arrayexpress
UnknownEffect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.
Not available
S-EPMC5710484 | biostudies-literature
UnknownLatin American Surgical Outcomes Study in Paediatrics (LASOS-Peds): study protocol and statistical analysis plan for a multicentre international observational cohort study.
Not available
S-EPMC11418559 | biostudies-literature
UnknownDifferentiation of COVID-19 signs and symptoms from allergic rhinitis and common cold: An ARIA-EAACI-GA2 LEN consensus.
Not available
S-EPMC8250633 | biostudies-literature
UnknownEpidemiology, ventilation management and outcomes of COVID-19 ARDS patients versus patients with ARDS due to pneumonia in the Pre-COVID era.
Not available
S-EPMC11330602 | biostudies-literature
UnknownMethodological considerations in injury burden of disease studies across Europe: a systematic literature review.
Not available
S-EPMC9382747 | biostudies-literature
UnknownDeath following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
Not available
S-EPMC10364875 | biostudies-literature
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