Aim: to study gene expression changes induced when in vitro cultures of normal human urothelial cells are induced to differentiate using two previously published methods: Varley et al (2004) and Cross et al (2005)
Bulk RNA-seq profiling of untreated human cell lines derived from blood, breast and bladder tissues (MCF7, MDA-MB-231, KMCB2, Jurkat) to characterise baseline transcriptional differences across cellular contexts.