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ProteomicsMutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy
Mitochondrial cardiomyopathies are fatal diseases, with no effective treatment. Alterations of heart mitochondrial function activate the mitochondrial integrated stress response (ISRmt), a transcriptional program affecting cell metabolism, mitochondrial biogenesis, and proteostasis. In humans, mutat...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-01 | PXD031444 | Pride
Chchd10 Mitochondria Cardiomyopathy 
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