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MetabolomicsSpatial metabolomics of in situ, host-microbe interactions (MALDI imaging MS assay)
Spatial metabolomics describes the location and chemistry of small molecules involved in metabolic phenotypes, defense molecules and chemical interactions in natural communities. Most current techniques are unable to spatially link the genotype and metabolic phenotype of microorganisms in situ at a ...
2019-11-15 | MTBLS744 | MetaboLights
MetabolomicsSpatial metabolomics of in situ, host-microbe interactions (UPLC-MS/MS assay)
Spatial metabolomics describes the location and chemistry of small molecules involved in metabolic phenotypes, defense molecules and chemical interactions in natural communities. Most current techniques are unable to spatially link the genotype and metabolic phenotype of microorganisms in situ at a ...
2019-11-15 | MTBLS746 | MetaboLights
MetabolomicsSpatial metabolomics of in situ, host-microbe interactions (On-tissue MALDI imaging MS/MS assay)
Spatial metabolomics describes the location and chemistry of small molecules involved in metabolic phenotypes, defense molecules and chemical interactions in natural communities. Most current techniques are unable to spatially link the genotype and metabolic phenotype of microorganisms in situ at a ...
2019-11-15 | MTBLS805 | MetaboLights
MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
TranscriptomicsSpatial transcriptomics and proteomics of post-transplant HCC recurrence using 10x Visium CytAssist
Post-transplant hepatocellular carcinoma (HCC) recurrence is a devastating disease with an abysmal prognosis and no established treatment or prevention options. We performed spatial analysis to profile the tumor immune microenvironment in primary HCC at liver transplantation and in recurrent HCC at ...
ORGANISM(S): Homo sapiens 
2026-04-01 | E-MTAB-15756 | biostudies-arrayexpress
UnknownAn Ultrasensitive Spatial Tissue Proteomics Workflow Exceeding 100 Proteomes Per Day.
Not available
S-EPMC12828817 | biostudies-literature
UnknownSpatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Not available
S-EPMC12759074 | biostudies-literature
UnknownA Standardized and Reproducible Workflow for Membrane Glass Slides in Routine Histology and Spatial Proteomics.
Not available
S-EPMC10565769 | biostudies-literature
ProteomicsSpatial SILAC Regorafenib Treated Bottom-up Proteomic Analysis
Developing effective model systems to evaluate new potential chemotherapeutic reagents is critical. Three-dimensional cell cultures, such as spheroids, aid in bridging the gap between commonly used monolayer cell cultures and significantly more complex and expensive animal models. Spheroid model sys...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD038958 | Pride
Spatial silac Regorafenib Spheroids 
ProteomicsBottom-up spatial proteomics MALDI MSI
New workflow for spatial bottom-up proteomics at single-cell resolution.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056528 | Pride
Maldi msi Spatial proteomics 
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