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ProteomicsMaTAR25 RNA Antisense Pulldown and Mass Spectrometry
It has been suggested that lncRNAs can interact with transcriptional regulators/co-factors to form ribonucleoprotein (RNP) complexes to regulate the expression of downstream genes in the cell nucleus. To identify potential interacting proteins of MaTAR25, we used two different paired sets of biotin-...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-23 | PXD017398 | Pride
Breast cancer Mouse Protein interaction Lncrna Biotin-oligos Matar25 
TranscriptomicsDifferentiation of Mammary Tumors and Reduction in Metastasis Upon Malat1 LncRNA Loss
Genome-wide analyses have identified thousands of long non-coding RNAs (lncRNAs). Malat1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) is among the most abundant lncRNAs whose expression is altered in numerous cancers. Here we report that genomic loss, as well as systemic knockdown of Mal...
ORGANISM(S): Mus musculus 
2016-01-12 | E-GEOD-67647 | biostudies-arrayexpress
TranscriptomicsRole of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation (4C-seq)
Cancer cells frequently depend on chromatin regulatory activities to maintain a malignant phenotype. Here, we show that leukemia cells require the mammalian SWI/SNF chromatin remodeling complex for their survival and aberrant self-renewal potential. While Brg1, an ATPase subunit of SWI/SNF, is known...
ORGANISM(S): Mus musculus 
2013-12-02 | E-GEOD-52595 | biostudies-arrayexpress
TranscriptomicsQuantitative analysis of chromatin interactions upon copy number variation at mouse 4E2 [4C-seq]
The three-dimensional organization of chromatin has a critical impact on the regulation of gene expression. However, little is known about the effect of DNA copy number variants (CNVs) on chromatin organization. We performed an allele-specific chromatin conformation and gene expression analysis of w...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-64358 | biostudies-arrayexpress
TranscriptomicsQuantitative analysis of chromatin interactions upon copy number variation at mouse 4E2 [RNA-seq]
The three-dimensional organization of chromatin has a critical impact on the regulation of gene expression. However, little is known about the effect of DNA copy number variants (CNVs) on chromatin organization. We performed an allele-specific chromatin conformation and gene expression analysis of w...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-64359 | biostudies-arrayexpress
UnknownAdjuvant Olaparib for Patients with <i>BRCA1</i>- or <i>BRCA2</i>-Mutated Breast Cancer.
Not available
S-EPMC9126186 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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