Spermatogenic injury

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Unknown (38)
Genomics (5)
Transcriptomics (4)
Proteomics (2)
Metabolomics (1)

Organisms

Mus musculus (4)
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uncultured environmental isolates (1)
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Cynomolgus macaque cytomegalovirus strain Mauritius (1)
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peste-des-petits-ruminants virus (1)
Mylodontidae (1)
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Megalonychidae (1)
Coxiella burnetii RSA 331 (1)

Organisms

Mus musculus (2)
Rattus norvegicus (1)

Repository

ENA (5)
geo (3)
biostudies-arrayexpress (1)
iProX (1)
MetaboLights (1)
pride (1)

Tissue

Testis (1)

Technology Type

Mass spectrometry (1)
Data-independent acquisition (1)
Mass Spectrometry (1)

Instrument Platform

Liquid Chromatography MS - negative (1)
Liquid Chromatography MS - positive (1)

Publication Date

2026 (2)
2025 (2)
2008 (1)
2018 (1)

Metabolite Name

Azulene, 1,4-dimethyl-7-(1-methylethyl)- (1)
7-[2-[(4aS,8aS)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-2-oxoethoxy]-3,4-dimethylchromen-2-one (1)
2-Acetamido-3-(1,3-Benzodioxol-5-Yl)-N-(Phenylmethyl)-2-Propenamide (1)
3-hydroxy-4-methoxy-2,3-dihydropyran-6-one (1)
(1,3-dimethyl-2,6-dioxo(1,3-dihydropyrimidin-4-yl))-N-[2-(2-chlorophenoxy)ethy l]carboxamide (1)
Methyl 1-(4-fluorophenyl)-1,2,3,4-tetrahydrobeta-carboline-3-carboxylate (1)
1,4-Ethanonaphthalene-5,10-dicarboxylic acid, 1,4,4a,5,6,8a-hexahydro-5,10-dihydroxy-6,9-dioxo-, bis[[2-(beta-D-glucopyranosyloxy)-3-hydroxyphenyl]methyl] ester (1)
1-{[(3-Cyano-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-2-Yl)Sulfanyl]Acetyl}Proline (1)
Spegatrine (1)
1-(2,5-diphenyl(1,3-oxazol-4-yl))-5-chloro-1,3-dihydropyrimidine-2,4-dione (1)
N-(2-furylmethyl)(2-oxochromen-3-yl)carboxamide (1)
Chlorothalonil TP SYN548008 (1)
Agatholal (1)
Coumaroyl Hexoside (1)
N-(2,5-dimethoxyphenyl)-2-[2-oxo-4-(piperidylcarbonyl)hydroquinolyl]acetamide (1)
Crocin II (1)
(8aR,12S,12aR)-12-hydroxy-4-methyl-4,5,6,7,8,8a,12,12a-octahydro-1H-3-benzoxecine-2,9-dione (1)
Methyl 4-[(3,4,5-trimethoxyphenyl)carbonylamino]benzoate (1)
3',4',5',6' tetradehydrolongicaudatine Y (1)
Dendrophenol (1)
Methyl (2E,3E,5E,7E,9E)-2-Ethylidene-11-[(1R,5R)-4-Hydroxy-4-(2-Hydroxyethyl)-2-Oxo-6-Oxa-3-Azabicyclo[3.1.0]Hexan-1-Yl]-4,10-Dimethyl-11-Oxoundeca-3,5,7,9-Tetraenoate (1)
Phenyl beta-D-glucopyranosiduronic acid (1)
(2E)-1-{2-[4-(diethylamino)phenyl]-6-hydroxy-3-azabicyclo[4.4.0]dec-3-yl}-3-(3 ,4-dimethoxyphenyl)prop-2-en-1-one (1)
1-Boc-4-Phenyl-DL-Proline (1)
N-(2,6-dimethylphenyl)-2-[2-oxo-4-(N-propylcarbamoyl)hydroquinolyl]acetamide (1)
1-acetyl-4-[(4-chlorophenyl)methoxy]-3-methoxybenzene (1)
Mono(2-ethyl-5-hydroxyhexyl) phthalate (1)
Octylphenazolone (1)
4-Hydroxy-4-(hydroxymethyl)-6,6-dimethyl-3-oxo-1,3,4,5,6,7,7a,9a-octahydropentaleno[1,6a-c]pyran-9-carboxylic acid (1)
Alpha-Ketoisovalerate (1)

First Public Date

2026 (3)
2025 (1)
2019 (1)

Study type

Transcription profiling by array (1)

Release Date

2025 (7)
2022 (7)
2021 (6)
2024 (4)
2020 (4)
2014 (3)
2026 (2)
2016 (2)
2008 (1)
2023 (1)
2019 (1)
2017 (1)

Lab affiliation

Department of Biochemistry and Molecular Biology, State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing 100005, China (1)

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Human umbilical cord multipotent mesenchymal stromal cells alleviate acute ischemia-reperfusion injury of spermatogenic cells via reducing inflammatory response and oxidative stress.

Not available

S-EPMC7366899 | biostudies-literature

SRP Rescues Spermatogenic Injury

To elucidate the molecular reprogramming within testicular tissue underlying this phenotype, the three groups (BO, CO, and SRP400) with the most pronounced model injury and rescue effects were subjected to parallel transcriptomic, DIA proteomic, and untargeted metabolomic analyses, with six testicul...

ORGANISM(S): Mus Musculus

PXD084866 |

Competition for mitogens regulates spermatogenic stem cell homeostasis in an open niche

PRJNA486990 | ENA

Intravenous Administration of Stromal Vascular Fraction Attenuates Early Busulfan-Induced Testicular Injury in Rats: An Alternative Cell-Based Approach for Spermatogenic Impairment

PRJNA1499255 | ENA

Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche.

Not available

S-EPMC6327111 | biostudies-literature

Competition for mitogens regulates spermatogenic stem cell homeostasis in an open niche

In many tissues, homeostasis is maintained by physical contact between stem cells and an anatomically-defined niche. However, how stem cell homeostasis is achieved in environments where cells are motile and dispersed among their progeny remains unknown. Using murine spermatogenesis as a model, we fi...

ORGANISM(S): Mus musculus

2018-12-19 | GSE118846 | GEO

ICA II Alleviates Testicular Torsion Injury by Dampening the Oxidative and Inflammatory Stress.

Not available

S-EPMC9135456 | biostudies-literature

Proteomic analysis for Cisplatin -induced mice spermatogenesis defects

Cisplatin is a crucial chemotherapeutic agent for treating various cancers, but excessive use can cause irreversible damage to the reproductive system. However, the protein expression profile of cisplatin-induced testicular injury remains poorly understood. In this study, we observed that cisplatin ...

ORGANISM(S): Mus musculus (Mouse)

2025-11-03 | PXD061652 | Pride

Adipose Mesenchymal Stromal Cell-Derived Exosomes Prevent Testicular Torsion Injury via Activating PI3K/AKT and MAPK/ERK1/2 Pathways.

Not available

S-EPMC9225846 | biostudies-literature

Testicular injury during SARS-CoV-2 infection may be neglected: An assessment from scRNA-seq profiling and protein detection of angiotensin-converting enzyme II.

Not available

S-EPMC8576622 | biostudies-literature

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