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P. falciparum blood stage parasites maintain an intricate system of membranes, requiring precise mechanisms of lipid synthesis and trafficking. Lipid transfer proteins (LTPs) at interorganelle membrane contact sites (MCSs) have emerged as key for ensuring proper lipid distribution in cells but so fa...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2025-07-28 | PXD066159 | Pride
PfEMP1 is the major virulence factor of Plasmodium falciparum parasites. PfEMP1 is expressed as an integral membrane protein on the surface of infected red blood cells. As a part of this project, the BioID system was utilized to biotinylate proximal proteins of a functional PfEMP1. In order to do th...
ORGANISM(S): Plasmodium falciparum 
2025-11-13 | PXD052297 | Pride
As part of a larger study characterizing all unknown 'nonsecretory' proteins encoded on chromosome 3 of P. falciparum parasites, we selected two candidate proteins (Chr3C7 and Chr3C16) to obtain interactomes using dimerisation-induced quantitative BioID (DiQ-BioID). This set of experiments r...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2023-02-17 | PXD035332 | Pride
In order to identify Kelch13 interaction partners in living P. falciparum parasites, we established a new type of BioID we termed dimerisation-induced quantitative BioID (DiQ-BioID) that takes advantage of the FKBP-FRB heterodimerisation system. For DiQ-BioID the target is endogenously tagged with F...
ORGANISM(S): Plasmodium falciparum 
2021-12-02 | PXD008219 | Pride
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