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TranscriptomicsConstraint and divergence of global gene expression in the mammalian embryo
We profiled genome-wide gene expression of 170 individual mid-gestation (embryonic day 11.5) whole mouse embryos derived from a 2-generation interspecies mouse cross and asked to what extent genetic variation drives four important parameters of regulatory architecture: allele-specific expression (AS...
ORGANISM(S): Mus musculus 
2015-04-14 | E-GEOD-62967 | biostudies-arrayexpress
TranscriptomicsGlobal analyses of how 3' UTR-isoform choice influences mRNA stability and translational efficiency
We obtained global measurements of decay and translation rates for mammalian mRNAs with alternative 3' untranslated regions (3' UTRs). 1 3P-Seq sample from 3T3 cells and 1 3P-Seq sample from mouse ES cells; 2 2P-Seq steady state and 4 2P-Seq with actinomycin D; 6 polysome fraction 2P-Seq
ORGANISM(S): Mus musculus 
2013-02-28 | E-GEOD-44698 | biostudies-arrayexpress
TranscriptomicsMammalian microRNAs: Experimental evaluation of novel and previously annotated genes
MicroRNAs (miRNAs) are small regulatory RNAs that derive from distinctive hairpin transcripts. To learn more about the miRNAs of mammals, we sequenced 60 million small RNAs from mouse brain, ovary, testes, embryonic stem cells, three embryonic stages, and whole newborns. Analysis of these sequences ...
ORGANISM(S): Homo sapiens 
2010-04-26 | E-GEOD-20384 | biostudies-arrayexpress
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