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TranscriptomicsComparative analysis of Drd1+ Medium Spiny Neurons and Drd2+ Medium Spiny Neurons
The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations. Using Bacterial Artificial Chromosome (BAC) transgenic mice which express EGFP-tagged ribosomal protein L10a in defined cell populations, we have developed a methodology...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13384 | biostudies-arrayexpress
TranscriptomicsComparative analysis of Drd1+ Medium Spiny Neurons, Drd2+ Medium Spiny Neurons, cocaine treatment
The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations. Using Bacterial Artificial Chromosome (BAC) transgenic mice which express EGFP-tagged ribosomal protein L10a in defined cell populations, we have developed a methodology...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13386 | biostudies-arrayexpress
TranscriptomicsComparative analysis of Drd1+ Medium Spiny Neurons, Drd2+ Medium Spiny Neurons, Motor Neurons, and Purkinje Neurons
The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations. Using Bacterial Artificial Chromosome (BAC) transgenic mice which express EGFP-tagged ribosomal protein L10a in defined cell populations, we have developed a methodology...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13387 | biostudies-arrayexpress
TranscriptomicsMouse Gpr88
Gpr88 is an orphan G protein-coupled receptor highly expressed in the striatum, a region important for motor control and learning. We developed a mouse lacking this receptor (genotype Gpr88Cre/Cre) by replacing most of the open-reading-frame of the Gpr88 gene with Cre recombinase. When comparing th...
ORGANISM(S): Mus musculus 
2012-10-15 | E-MTAB-1282 | biostudies-arrayexpress
ModelsYapo2017- cAMP/PKA signalling in D1 dopamine receptor expressing medium-spiny neurons
Yapo2017- cAMP/PKA signalling in D1 dopamine receptor expressing medium-spiny neurons This model is described in the article: Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons. Yapo C, Nair AG, Clement L, Castro LR, Hellgren Kotaleski J, Vincent P. J. Phy...
2017-08-16 | MODEL1701170000 | BioModels
ModelsYapo2017 - A2AR/cAMP/PKA signalling in D2 dopamine receptor expressing medium-spiny neurons
Yapo2017 - A2AR/cAMP/PKA signalling in D2 dopamine receptor expressing medium-spiny neurons This model is described in the article: Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons. Yapo C, Nair AG, Clement L, Castro LR, Hellgren Kotaleski J, Vincent P. ...
2017-08-16 | MODEL1701170001 | BioModels
TranscriptomicsTranscription profiling of mouse wild type and Ctip2-/- (Bcl11b) mutant striatum at P0
Striatal medium spiny neurons (MSN) are critically involved in motor control, and their degeneration is a principal component of Huntington’s disease. We find that the transcription factor Ctip2 (also known as Bcl11b) is central to MSN differentiation and striatal development. Within the striatum,...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9330 | biostudies-arrayexpress
GenomicsSpiny mice genomes
Spiny mice genome project leaded by EMBL-EBI and Wellcome Sanger Institute
PRJEB44012 | ENA
UnknownIschemic tolerance and cardiac repair in the spiny mouse (Acomys).
Not available
S-EPMC8599451 | biostudies-literature
UnknownDe novo transcriptome assembly for the spiny mouse (Acomys cahirinus).
Not available
S-EPMC5566366 | biostudies-literature
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