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UnknownGenomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2(-•) and H2O2.
Not available
S-EPMC3249516 | biostudies-literature
TranscriptomicsGenome-wide screen for salmonella genes required for long-term systemic infection of the mouse.
This datasets includes all arrays from the first passage through 129SvJ mice (28 days) and the second independent passage (29 days). The first passage arrays are the same as included in the experiment set "129SvJ Pass 1 28 dpi arrays" and the second passage arrays are the same as included...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2006-03-14 | E-GEOD-4461 | biostudies-arrayexpress
TranscriptomicsTimecourse expression data from sciatic nerve distal stump of C57BL/6 and C57BL/6 OlaHsd-Wlds mice.
Wallerian degeneration (WD) involves the fragmentation of axonal segments disconnected from their cell bodies, segmentation of the myelin sheath, and removal of debris by Schwann cells and immune cells. The removal and downregulation of myelin-associated inhibitors of axonal regeneration and synthes...
ORGANISM(S): Mus musculus 
2011-06-01 | E-GEOD-22291 | biostudies-arrayexpress
TranscriptomicsTranscription profling of human neuroblastoma samples to construct, validate and evalute a gene expression based classification of outcome of treatment
This set of 320 profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients
ORGANISM(S): Homo sapiens 
2009-02-17 | E-TABM-38 | biostudies-arrayexpress
UnknownPaclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2-mediated oxidative stress.
Not available
S-EPMC2843822 | biostudies-literature
UnknownSirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.
Not available
S-EPMC3266626 | biostudies-literature
TranscriptomicsTranscription profiling of Salmonella passaged through 129SvJ mice to identify genes required for long term systemic infection
This experiment set includes all the input and spleen pooled arrays from the first negative selection passaged through 129SvJ mice and represents the 28-day timepoint. "P.2 input" is the same thing as the P.1 output while "P.2 output" represents a sample of the 28-day output repassaged through mice...
ORGANISM(S): Salmonella enterica serovar Typhimurium 
2006-06-06 | E-SMDB-3619 | biostudies-arrayexpress
UnknownAvasopasem manganese (GC4419) protects against cisplatin-induced chronic kidney disease: An exploratory analysis of renal metrics from a randomized phase 2b clinical trial in head and neck cancer patients.
Not available
S-EPMC9852651 | biostudies-literature
UnknownPersistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease.
Not available
S-EPMC6174865 | biostudies-literature
Transcriptomicsc-JUN REPROGRAMS SCHWANN CELLS OF INJURED NERVES TO GENERATE A REPAIR CELL ESSENTIAL FOR REGENERATION
The striking PNS regenerative response to injury rests on the plasticity of adult Schwann cells and their ability to transit between differentiation states, a highly unusual feature in mammals. Using mice with inactivation of Schwann cell c-Jun, we show that the injury response involves c-Jun depen...
ORGANISM(S): Mus musculus 
2012-06-13 | E-GEOD-38693 | biostudies-arrayexpress
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