Genome-wide screen for salmonella genes required for long-term systemic infection of the mouse.

ABSTRACT: This datasets includes all arrays from the first passage through 129SvJ mice (28 days) and the second independent passage (29 days). The first passage arrays are the same as included in the experiment set "129SvJ Pass 1 28 dpi arrays" and the second passage arrays are the same as included in the experiment set "129SvJ Pass 2 28 dpi arrays". Input arrays are also included and collectively they represent two biological replicates for negative selection at ~4 weeks post infection. Abstract: A microarray-based negative selection screen was performed to identify Salmonella enterica serovar Typhimurium (serovar Typhimurium) genes that contribute to long-term systemic infection in 129X1/SvJ (Nramp1(r)) mice. A high-complexity transposon-mutagenized library was used to infect

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium

SUBMITTER: Kaman Chan 

PROVIDER: E-GEOD-4461 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress