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TranscriptomicsMicroRNA profiling of HCT-116 versus HCT-116 treated with 5-aza-2'-deoxycytidine processing human colon cancer cell lines
UCRs expression signature of HCT-116 cell lines versus HCT-116 cell line treated with DNA methylation inhibitor 5-aza-2'-deoxycytidine
ORGANISM(S): Homo sapiens 
2010-03-09 | E-MTAB-196 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human colorectal cancer samples with high microsatellite instability
Background. Colorectal cancer develops through two main genetic instability pathways characterized by distinct pathologic features and clinical outcome. Results. We investigated colon cancer samples (23 characterized by microsatellite stability, MSS, and 16 by high microsatellite instability, MSI-H)...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-TABM-326 | biostudies-arrayexpress
TranscriptomicsModulation of microRNA-194 and Cell Migration by HER2-targeting Trastuzumab in Breast Cancer
We found that trastuzumab (herceptin) treatment significantly decreased five miRNAs and increased three others in SKBr3 cells, whereas in BT474 cells it significantly decreased two miRNAs and increased nine. The only miRNA that shared the same change in both cell lines was miRNA-194 (miR-194), which...
ORGANISM(S): Homo sapiens 
2013-01-31 | E-MTAB-965 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancer cell lines and tissue samples to identify aberrant microRNA expression
MicroRNAs are a class of small non-coding RNAs that control gene expression by targeting messenger RNAs and triggering either translation repression or RNA degradation. Their aberrant expression may be involved in human diseases, including cancer. Indeed, microRNA aberrant expression has been previo...
ORGANISM(S): Homo sapiens 
2006-01-01 | E-TABM-23 | biostudies-arrayexpress
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