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Attention to exploring endothelial cell (EC) metabolism is increasing, but a holistic perspective on the metabolic adaptations of ECs during angiogenic proliferation, is still missing. Here, we use a previously in-house developed computational EC-adapted genome scale metabolic model that recapitulat...
2026-08-10 | MTBLS15306 | MetaboLights
Cx40 Suppresses Sprouting Angiogenesis In Vitro
The paper describes a model of tumor growth with angiogenesis. Created by COPASI 4.26 (Build 213) This model is described in the article: Mathematical modeling of solid cancer growth with angiogenesis Hyun M Yang Theoretical Biology and Medical Modelling 2012, 9:2 Abstract: Background: Cance...
2024-09-02 | BIOMD0000000796 | BioModels
The histone acetyltransferase HBO1 (KAT7) promotes efficient tip cell sprouting during angiogenesis
The histone acetyltransferase HBO1 (KAT7) promotes efficient tip cell sprouting during angiogenesis
Blood vessels are highly organized and form during development through a series of complex processes that include vasculogenesis, sprouting angiogenesis, and vessel remodeling. Several gap junction proteins (termed connexins, Cx) – including Cx40 (GJA5) – are expressed in vascular endothelium early ...
ORGANISM(S): Homo sapiens 
2023-12-14 | GSE243404 | GEO
A Regulatory microRNA Network Controls Endothelial Cell Phenotypic Switch During Sprouting Angiogenesis [2D]
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