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Label the cells overexpressed Flag tagged YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 and SRSF10 with 4-SU, the RNA bound by YTHDC1 and SRSF proteins can be got by Flag IP followed by RNA isolation by using the TRIzol (Invitrogen) reagent by following the company manual.the RNA was then used for library prep...
ORGANISM(S): Homo sapiens 
Genomics
Aberrant splicing in livers of SRSF KO mice
This SuperSeries is composed of the SubSeries listed below.
ORGANISM(S): Mus musculus 
2015-05-01 | GSE57021 | GEO
Transcribed CGG repeat expansions cause the neurodegenerative disorder Fragile X-associated tremor/ataxia syndrome (FXTAS). CGG repeat RNAs sequester RNA-binding proteins (RBPs) into nuclear foci and undergo repeat-associated non-AUG (RAN) translation into toxic peptides in the cytoplasm. To identif...
ORGANISM(S): Homo sapiens (Human) 
2021-09-28 | PXD027000 | Pride
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