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ProteomicsSOX11-SMARCA4 Complex Drives Oncogenic Gene Regulation in Mantle Cell Lymphoma
SOX11 pioneer transcription factor is aberrantly expressed, it has an oncogenic role and its overexpression associates with worse prognosis in patients with mantle cell lymphomas (MCL). Using a proximity labeling (BioID2)/Mass Spectrometry-based proteomic strategyies, we identified SMARCA4, the cent...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD051143 | Pride
Smarca4 Cut&run-sequencing. Sry-related hmg-box 11 (sox11) Mantle cell lymphoma Swi/snf chromatin remodeling complex Pioneer transcription factor 
TranscriptomicsExpression data from E18 mouse embryonic retina in wild-type mouse and Sox11 knockout mouse
The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells. Sry-related HMG box (Sox) proteins play diverse and critical roles in a variety of morphogenetic processes during embryonic development. Sox11 and Sox4 are members of the SoxC subtype, an...
ORGANISM(S): Mus musculus 
2012-12-28 | E-GEOD-43089 | biostudies-arrayexpress
GenomicsEpigenetic changes cause aberrantly high expression of SOX11 leading to systemic sclerosis
Systemic sclerosis (SSc) is a chronic, heterogenous multisystem connective tissue disease characterized by vascular injury, autoimmunity, and organ fibrosis. Epigenetic modification is thought to be important in the onset and progression of SSc. SOX (SRY-related HMG box) 11 is a transcription factor...
ORGANISM(S): Homo sapiens 
2025-01-15 | GSE268765 | GEO
UnknownSOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma.
Not available
S-EPMC11103171 | biostudies-literature
GenomicsEpigenetic changes cause aberrantly high expression of SOX11 leading to systemic sclerosis
Epigenetic changes cause aberrantly high expression of SOX11 leading to systemic sclerosis
PRJNA1118702 | ENA
UnknownCase Report: Observation of early-onset high myopia with fundus tessellation changes in Coffin-Siris syndrome 9 (CSS9) and literature review.
Not available
S-EPMC12417530 | biostudies-literature
UnknownThe Expression Level of SOX Family Transcription Factors' mRNA as a Diagnostic Marker for Osteoarthritis.
Not available
S-EPMC11856735 | biostudies-literature
UnknownFirst observation of secondary childhood glaucoma in Coffin-Siris syndrome: a case report and literature review.
Not available
S-EPMC7802219 | biostudies-literature
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