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TranscriptomicsSSEA-4 labels a subset of poor prognosis-associated osteosarcoma-initiating cells that respond to differentiation induction
Osteosarcoma is thought of arising from the malignant transformation of osteogenic progenitors. The stage-specific embryonic antigen-4 (SSEA-4) labels a subset of TICs specially present in the high-risk subgroup. SSEA-4+ AND SSEA-4-
ORGANISM(S): Homo sapiens 
2014-06-05 | E-GEOD-58209 | biostudies-arrayexpress
UnknownmTORC1 maintains the tumorigenicity of SSEA-4(+) high-grade osteosarcoma.
Not available
S-EPMC4389812 | biostudies-literature
UnknownDevelopment of Fluorescently Labeled SSEA-3, SSEA-4, and Globo-H Glycosphingolipids for Elucidating Molecular Interactions in the Cell Membrane.
Not available
S-EPMC6941013 | biostudies-literature
UnknownAberrant SSEA-4 upregulation mediates myofibroblast activity to promote pre-cancerous oral submucous fibrosis.
Not available
S-EPMC5109465 | biostudies-literature
UnknownExpression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells.
Not available
S-EPMC4565992 | biostudies-literature
TranscriptomicsSSEA-4 labels a subset of poor prognosis-associated osteosarcoma-initiating cells that respond to differentiation induction
Osteosarcoma is thought of arising from the malignant transformation of osteogenic progenitors. The stage-specific embryonic antigen-4 (SSEA-4) labels a subset of TICs specially present in the high-risk subgroup.
ORGANISM(S): Homo sapiens 
2014-06-05 | GSE58209 | GEO
UnknownLectin binding profiles of SSEA-4 enriched, pluripotent human embryonic stem cell surfaces.
Not available
S-EPMC1182361 | biostudies-literature
UnknownStemness properties of SSEA-4+ subpopulation isolated from heterogenous Wharton's jelly mesenchymal stem/stromal cells.
Not available
S-EPMC10917976 | biostudies-literature
TranscriptomicsDifferential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer model (SNP)
The cellular heterogeneity of one patient derived orthotopic breast cancer xenograft model PDX was investigated using flow cytometry, combined with assessment of in vivo tumorigenicity and SNP genotyping array for copy number analysis. Epithelial cell adhesion molecule (EpCAM) was revealed as a high...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-54595 | biostudies-arrayexpress
TranscriptomicsHuman bone-derived 11Lin-CD45-CD271+SSEA-4+ mesenchymal stem/stromal cells from young and elderly patients
Global gene expressions of human bone-derived 11Lin-CD45-CD271+SSEA-4+ mesenchymal stem/stromal cells from young and elderly patients were analyzed. Results provide an insight into the molecular mechanisms of aging and cellular senescence.
ORGANISM(S): Homo sapiens 
2017-07-21 | GSE101694 | GEO
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