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TranscriptomicsDNA copy number analysis of myxoinflammatory fibroblastic sarcoma, and morphologically similar lesions
DNA copy number analysis of myxoinflammatory fibroblastic sarcomas, and related lesions, using 32k BAC array CGH. All four cases analyzed with array CGH showed amplification of the region 86.30-87.74 Mb in 3p11.1-12.1. No additional aberration was detected in more than two tumors, except for the del...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-12593 | biostudies-arrayexpress
TranscriptomicsLandscape of somatic allelic imbalances and copy number alterations in human lung carcinoma
Lung cancer is the worldwide leading cause of death from cancer. This GEO series correspond to one of the BAC aCGH data sets used as validation cohort for the study: Landscape of somatic allelic imbalances and copy number alterations in human lung cancer, Int J Cancer 2012. Genomic profiling of 78 l...
ORGANISM(S): Homo sapiens 
2012-10-09 | E-GEOD-29065 | biostudies-arrayexpress
TranscriptomicsDetailed analysis of 6p and 1q amplifications in urothelial carcinoma reveals SOX4 as an auxiliary target on 6p, and BCL9, CHDL1, MCL1, SETDB1, and HIF1B as putative targets on 1q.
Background: Previous array CGH analyses have revealed several recurring genomic alterations in urothelial carcinoma. The most common genomic amplifications occur at 6p22 and 1q21-24. The main target gene at 6p22 is believed to be E2F3. This gene is frequently co-amplified with CDKAL1 and SOX4 and th...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-40938 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation analysis of lung carcinoma : Gene expression data
Lung cancer is the worldwide leading cause of death from cancer. DNA methylation in gene promoter regions is a major mechanism of gene expression regulation that may promote tumorigenesis. Experimental Design Whole-genome DNA methylation analysis using 450K Illumina BeadArrays was performed on ...
ORGANISM(S): Homo sapiens 
2014-10-05 | E-GEOD-60644 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation and expression analysis of lung carcinoma
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-10-05 | E-GEOD-60645 | biostudies-arrayexpress
TranscriptomicsHeterogeneous genetic profiles in soft tissue myoepitheliomas
Myoepithelioma, mixed tumor and parachordoma are rare soft tissue tumors thought to represent different morphologic variants of the same family of tumors, hereafter referred to as MMP tumors. The genetic basis of these neoplasms is poorly investigated. However, they morphologically resemble mixed tu...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-10266 | biostudies-arrayexpress
UnknownTumor purity adjusted beta values improve biological interpretability of high-dimensional DNA methylation data.
Not available
S-EPMC9462735 | biostudies-literature
UnknownConsensus of gene expression phenotypes and prognostic risk predictors in primary lung adenocarcinoma.
Not available
S-EPMC5288161 | biostudies-literature
TranscriptomicsIntegrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma (genomic)
Genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma 146 primary bladder cancer tumor samples were analyzed on BAC array containing ~32 000 BAC clones. Arrays were produced at the Swegene Centre for Integrative Biology at Lund University ...
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-32535 | biostudies-arrayexpress
TranscriptomicsNon-coding antisense transcription detected by conventional and single-stranded cDNA microarray
Recent bioinformatic studies revealed that many mammalian protein-coding genes also transcribe their complementary strands. This phenomenon raises questions regarding the validity of data obtained from double-stranded cDNA microarrays since hybridization to both strands may occur. To analyze experim...
ORGANISM(S): Homo sapiens 
2007-09-01 | E-GEOD-7860 | biostudies-arrayexpress
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