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In order to analyze HUVECs under normoxia and hypoxia, cells were initially deprived of excess nutrients and hormones by maintaining them overnight in a restricted medium with only 2% fetal bovine serum, and incubated for 40 hours in the presence of the tracer [1,2-13C2]-glucose until sample collect...
2017-12-18 | MTBLS412 | MetaboLights
Proper regulation of glycogen metabolism is fundamental to cellular energy homeostasis, and its disruption is associated with various metabolic disorders, including glycogen storage diseases (GSDs) and potentially diabetes. Despite glycogen’s role as an essential energy reservoir, the mechanisms gov...
2025-07-15 | MTBLS12586 | MetaboLights
The severe harm of depression to human life has attracted great attention to neurologists, but its pathogenesis is extremely complicated and has not yet been fully elaborated. Here, we provided a new strategy for revealing the specific pathways of abnormal brain glucose catabolism in depression, whi...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-06-10 | PXD025548 | Pride
The severe harm of depression on human life has attracted great attention. However, due to its unclear and extremely complex pathogenesis, the efficacy of existing marketed antidepressants is far from satisfactory. Consequently, it is urgent to understand the pathogenesis of depression from novel pe...
ORGANISM(S): Rattus Rattus 
2025-07-14 | PXD066143 |
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