Sort   by:  
 Page size 
MetabolomicsMetabolomic mechanisms of antimicrobial peptides against Helicobacter pylori

Metabolomic mechanisms of antimicrobial peptides against Helicobacter pylori. By establishing treatment and control models combined with untargeted metabolomic analysis, this study aims to reveal the key metabolic pathway alterations and metabolic network reprogramming induced by antimicrobial pe...

2026-02-10 | MTBLS13884 | MetaboLights
MetabolomicsLC–MS-Based Metabolomics Discriminates Premium from Standard Chilean cv. Cabernet Sauvignon Wines from Different Valleys

Cabernet Sauvignon grapes in Chile, mainly grown between the 30 °S and 36 °S, account for more than 30% of Chilean wine production, and yield wines with different characteristics which influence their quality. The aim of this study was to apply an LC-MS based metabolomic protocol to investigate t...

2022-01-28 | MTBLS2413 | MetaboLights
MetabolomicsCharacterization of active peptides derived from three leeches and comparison of their anti-thrombotic mechanisms using the tail vein thrombosis model in mice and metabonomics

BACKGROUND AND AIMS: The increasing incidence of cardiovascular diseases has created an urgent need for safe and effective anti-thrombotic agents. Leech, as a traditional Chinese medicine, has the effect of promoting blood circulation and removing blood stasis, but its real mater...

2024-01-18 | MTBLS9306 | MetaboLights
MetabolomicsAlleviation of high-fat diet-induced lipid metabolism disorders: Role of quinoa peptides in inhibiting high-activity BSH-producing gut microbiota and modulating of BA-FXR/TGR5 signaling
Abstract Background: Lipid metabolism disorders contribute significantly to various metabolic diseases and are closely related to gut microbiota dysbiosis. Our previous study showed that oral gavage of quinoa peptides (QPep) restored gut microbiota composition and alleviated liver lipid metabolism d...
2025-06-16 | MTBLS12584 | MetaboLights
TranscriptomicsNovel antioxidative peptides with potential to reduce psoriatic changes in PBMCs
Oxidative damage contributes significantly to the pathogenesis of psoriasis. We recently developed antioxidative peptides (UPF peptides) activating the endogenous glutathione system (GSH). In the present study, we analyzed gene expression profiles in the samples of psoriasis patients to find if thes...
ORGANISM(S): Homo sapiens 
2012-08-22 | E-GEOD-40263 | biostudies-arrayexpress
TranscriptomicsAnti-microbial peptides increase tolerance to oxidant stress in Drosophila melanogaster
It is well appreciated that reactive oxygen species (ROS) are deleterious to mammals, including humans, especially when generated in abnormally large quantities from cellular metabolism. Whereas the mechanisms leading to the production of ROS are rather well delineated, the mechanisms underlying tis...
ORGANISM(S): Drosophila melanogaster 
2010-12-21 | E-GEOD-23902 | biostudies-arrayexpress
MetabolomicsMetabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment

INTRODUCTION: The mitochondrial-derived peptides (MDPs) are a novel group of natural occurring peptides that have important signaling functions and biological activity. Both humanin and small-humanin-like peptide 2 (SHLP2) have been reported to act as insulin sensitizers and modu...

2019-06-21 | MTBLS159 | MetaboLights
ProteomicsLarge-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring
Development, implementation, and evaluation of a new data acquisition scheme called internal standard triggered-parallel reaction monitoring (IS-PRM) to increase the scale of targeted quantitative experiments while retaining high detection and quantification performance. All the details about the da...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080832 | MassIVE
ProteomicsA protein standard that emulates homology for the characterization of protein inference algorithms
A natural way to benchmark the performance of an analytical experimental setup is to use samples of known content, and see to what degree one can correctly infer the content of such a sample from the data. For shotgun proteomics, one of the inherent problems of interpreting data is that the measured...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
MSV000084315 | MassIVE
ProteomicsMedian Based Absolute Quantification using Fully Unlabelled Generic Internal Standard
By reporting molar abundances of proteins, absolute quantification determines their stoichiometry in complexes, pathways or networks and also relates them to abundances of non-protein biomolecules. Typically, absolute quantification relies either on protein- specific isotopically labelled peptide st...
ORGANISM(S): Homo sapiens (Human) Caenorhabditis elegans 
2021-11-30 | PXD026886 | Pride
Absolute quantification 
Sort   by:  
 Page size