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TranscriptomicsSwitching on antibiotic resistance in Staphylococcus aureus M-bM-^@M-^S Contribution of WalK and VraS histidine kinases in the development of vancomycin and daptomycin resistance
Staphylococcus aureus is a notorious bacterial pathogen that causes a broad range of human diseases, and isolates that are resistant to several antibiotic classes including last resort antibiotics like vancomycin and daptomycin complicate the situation. We characterized S. aureus VC40, a strain that...
ORGANISM(S): Staphylococcus aureus subsp. aureus Mu50 
2014-08-18 | E-GEOD-46887 | biostudies-arrayexpress
TranscriptomicsInhibition of Staphylococcus aureus biofilm formation by gurmarin, a plant-derived cyclic peptide
Staphylococcus aureus is an opportunistic pathogen capable of causing various infections ranging from superficial skin infections to life-threatening severe diseases, including pneumonia and sepsis. This bacterium is attached to biotic and abiotic surfaces and forms biofilms that are resistant to co...
ORGANISM(S): Staphylococcus aureus 
2022-09-21 | E-MTAB-12154 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of the eukaryotic-type ser/thr kinase PknB in Staphylococcus aureus
The function of the Staphylococcus aureus eukaryotic-like serine/threonine protein kinase PknB was investigated by transcriptome analysis using DNA-microarray technology and biochemical assays. The transcriptional profile reveals a strong regulatory impact of PknB on the expression of genes encoding...
ORGANISM(S): Staphylococcus aureus subsp. aureus NCTC 8325 
2010-05-05 | E-GEOD-15346 | biostudies-arrayexpress
TranscriptomicsExpression profiling of the Staphylococcus aureus GraSR regulon
The GraS/GraR two-component system has been shown to control cationic antimicrobial peptide (CAMP) resistance in the major human pathogen Staphylococcus aureus. We identified a highly conserved ten base pair palindromic sequence (5’ ACAAATTTGT 3’) located upstream from GraR-regulated genes (mprF and...
ORGANISM(S): Staphylococcus aureus 
2011-08-31 | E-GEOD-26016 | biostudies-arrayexpress
ProteomicsA global Staphylococcus aureus proteome resource applied to the in vivo characterization of host- pathogen interactions
1. DDA dataset used for Staphylococcus aureus HG001 PeptideAtlas build (https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=435) 2. DIA and DDA dataset for the quantitative analyses of the publication (in the update section)
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 (ncbitaxon:93061) Homo Sapiens (ncbitaxon:9606) 
2018-06-21 | MSV000082483 | MassIVE
GenomicsStaphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus NCTC 8325 Raw sequence reads
PRJNA279231 | ENA
GenomicsStaphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus NCTC 8325 Transcriptome or Gene expression
PRJNA1069972 | ENA
ProteomicsRepurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus
To combat methicillin-resistant Staphylococcus aureus (MRSA) infections novel drugs are desperately needed. From a screen, we found that the anti-cancer drug sorafenib effectively kills MRSA strains. By synthetic variation of key structural features, we identified a potent analog, PK150, exhibiting ...
ORGANISM(S): Staphylococcus aureus 
2019-09-09 | PXD012946 | Pride
Full proteome Affinity-based protein profiling (afbpp) Q exactive plus Chemical proteomics Staphylococcus aureus subsp. aureus nctc 8325 Secretome Surfaceome Orbitrap fusion 
GenomicsStaphylococcus aureus subsp. aureus NCTC 8325
Typical laboratory strain
PRJNA237 | ENA
ProteomicsIdentification of small proteins in Staphylococcus aureus
In this study, we have combined RNA-seq, Ribo-seq and shotgun proteomic analyses to identify and validate the expression of novel small proteins in Staphylococcus aureus.
ORGANISM(S): Staphylococcus aureus subsp. aureus NCTC 8325 Bacteria 
2025-09-22 | PXD061402 | Pride
Psms Sorf Small proteins Staphylococcus aureus 
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