Statins - OmicsDI

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CHEBI ID

CHEBI:16113 (3)
CHEBI:30794 (2)
CHEBI:17754 (2)
CHEBI:18050 (2)
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CHEBI:23623 (1)
CHEBI:144337 (1)
CHEBI:144336 (1)
CHEBI:144335 (1)
CHEBI:144333 (1)
CHEBI:144332 (1)
CHEBI:144331 (1)
CHEBI:144329 (1)

Metabolite Name

Tromethamine, 3TMS derivative (1)
Trimethylsilylpropargyl alcohol, 2TMS derivative (1)
Succinic acid, 2,2,3,3,4,4,5,5-octafluoropentyl 2-methylpent-3-yl ester (1)
Serine, 3TMS derivative (1)
Pyroglutamic acid, TMS derivative (1)
Propanoic acid, 3-[(tert-butyldimethylsilyl)oxy]-2-methyl-, tert-butyldimethylsilyl ester (1)
Propanedioic acid, 2TBDMS derivative (1)
Phthalic acid, di(3-methylphenyl) ester (1)
Phosphorylethanolamine, 4TMS derivative (1)
Phosphoric acid, bis[2,3-bis[(trimethylsilyl)oxy]propyl] trimethylsilyl ester (1)
Phosphonic acid, (aminomethyl)-, bis(trimethylsilyl) ester (1)
Phenylethyl Alcohol, TMS derivative (1)
Phenylalanine, 2TMS derivative (1)
Octanoic acid, tributylsilyl ester (1)
N-Acetyl-L-glutamic acid, 2TMS derivative (1)
N-.alpha.-Acetyl-L-Lysine, 3TMS derivative (1)
Myrtenoic acid, trimethylsilyl ester (1)
Monolaurin, 2TMS derivative (1)
Methyltris(trimethylsiloxy)silane (1)
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Mercaptoacetic acid, 2TMS derivative (1)
Malonic acid, bis(2-trimethylsilylethyl ester (1)
Lysine, 3TMS derivative (1)
L-Valine, TMS derivative (1)
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L-Proline, TMS derivative (1)
L-Proline, n-propargyloxycarbonyl-, propargyl ester (1)
L-Proline, 2TMS derivative (1)
L-Phenylalanine, 2TMS derivative (1)

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Lab affiliation

Associate Professor, Chemistry and Biochemistry, University of Texas at Arlington (1)
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Keyword

Genitourinary cancer (1)
Head and neck cancers (1)
Fish Oil supplement (1)
Statin (1)
Atorvastatin (1)
Lipitor (1)
Placebo (1)
ERAS (1)
Simvastatin (1)
Colorectal (1)
Colon (1)

IsPrivate

False (1)

Model Flag

Sbml Extended (1)
Non Kinetic (1)

Classification

fungi (2)

Study type

Transcription profiling by array (37)
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Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma

Relapse and treatment resistance are common in children with high-risk neuroblastoma, and novel therapies are needed. Conventional drug discovery is slow, expensive, often fails in practice, and consequently falls short in addressing pediatric and rare conditions. In such instances, drug repurpos...

2025-11-13 | MTBLS13246 | MetaboLights

Comparative Effects of Statins on Murine Cardiac Gene Expression Profiles in Normal Mice

Recent clinical data suggest that the efficacy of statin treatment in patients with heart failure varies depending on the drugs administered. Therefore, the present study was undertaken to compare murine cardiac gene expression following treatment with four different statins. Statins directly regula...

ORGANISM(S): Mus musculus

2013-03-31 | E-GEOD-23101 | biostudies-arrayexpress

Statins-induced changes in gene expression of pancreatic cancer cells with focus on anti-proliferative effects of statins.

Statins, potent lipid-lowering drugs, were also shown to exert anti-proliferative activity. The aim of this study was to identify the biological pathways affected by changes in gene expression activity after statins treatment and to compare the results with observed anti-proliferative effects. The s...

ORGANISM(S): Homo sapiens

2017-12-30 | E-MTAB-3979 | biostudies-arrayexpress

Statins affect gene expression in pancreatic cancer

PRJNA629289 | ENA

WTCCC2 Pharmacogenomic Response to Statins study

A WTCCC2 project genome-wide study for pharmacogenomic response to statins (PR) in individuals from Scotland.

EGAS00000000121 | EGA

Transcriptomic profile of human mesenchymal stem cells after statins treatment

Analysis of the effect of all available statins (atorvastatin, lovastatin, simvastatin, fluvastatin, cerivastatin, pravastatin, rosuvastatin, and pitavastatin) on the expression of genes in human cell cultures to investigate potential anti-inflammatory effect during COVID-19 disease. Transcription p...

ORGANISM(S): Homo sapiens

2024-01-01 | E-MTAB-11579 | biostudies-arrayexpress

PGRN – RIKEN: Genetic Determinants of Clinical Cardiovascular Events in Patients Receiving Statins

PRJNA290826 | ENA

Statins affect gene expression in pancreatic cancer

The statin family of cholesterol-lowering drugs was shown to influence the risk of multiple types of cancers. However, the anti-tumor effects of statins in pancreatic cancer and their efficacy differs among the individual statins, are not currently well-defined. Thus, the aim of the present study wa...

ORGANISM(S): Homo sapiens

2020-04-30 | GSE149566 | GEO

The transcriptional response of C. elegans to statins: general and p38 dependent responses

PRJNA548517 | ENA

Regulation of leukemic cell differentiation and retinoid-induced gene expression by statins

There is emerging evidence that, beyond their cholesterol lowering properties, statins exhibit important antileukemic effects in vitro and in vivo, but the precise mechanisms by which they generate such responses remain to be determined. We have previously shown that statins promote differentiation ...

ORGANISM(S): Homo sapiens

2009-01-20 | GSE12870 | GEO

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